One new macrolide sumatraenseride (1), along with four known macrolides (2–5) and one polyketide (6), was isolated from a strain of the fungus, Penicillium sp. SO02. The structure of 1 was elucidated by IR, UV, HR-ESI-MS, NMR spectra, and CD data. The cytotoxic activities of compound 1 against three human tumor cell lines were also tested, with IC50 values of 6.32 μM (HepG2), 18.38 μM (A875), and 90.23 μM (H460).
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Published in Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2023, pp. 277–279.
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Sang, Y., Wang, J., Tang, S. et al. A New Macrolide from Penicillium sp. SO02. Chem Nat Compd 59, 327–330 (2023). https://doi.org/10.1007/s10600-023-03986-w
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DOI: https://doi.org/10.1007/s10600-023-03986-w