A new eudesmane-type sesquiterpenoid, artemihedinic acid N (1), together with four known compounds, aspterric acid (2), two naphtho-γ-pyrones, peninaphones A (3) and B (4), and a diphenyl ether (5), were isolated from the rice medium fermentations of the mangrove rhizosphere soil-derived fungus Penicillium sp. HK1-22. The structure of 1 was determined by combined spectroscopic methods including 1D and 2D NMR spectral data. The antibacterial activities of all isolated metabolites were evaluated.
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The National Natural Science Foundation of China (No. 81703411) supported this work.
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Published in Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2023, pp. 241–243.
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Ji, RN., Wu, JT., Hao, BC. et al. A New Eudesmane Sesquiterpenoid from the Marine-Derived Fungus Penicillium sp. HK1-22. Chem Nat Compd 59, 285–287 (2023). https://doi.org/10.1007/s10600-023-03978-w
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DOI: https://doi.org/10.1007/s10600-023-03978-w