Pairs of enantiomeric phenylpropanoid glycosides and their aglycones, (8R)-stroside A (1), (8S)-stroside A (2), (8R)-evofolin B (3), and (8S)-evofolin B (4), were isolated from the hook-bearing stems of Uncaria rhynchophylla (Miq.) Miq. ex Havil. Among of these compounds, (8R)-stroside A (1) was a new one, and other known compounds were isolated from the genus Uncaria for the first time. The structure of the new compound was elucidated by extensive analysis of MS, 1D and 2D NMR, and ECD data.
Similar content being viewed by others
References
C. E. Ridsdale, Blumea, 4, 43 (1978).
Chinese Pharmacopoeia Commission, Chinese Pharmacopoeia, China Medical Science Press, Beijing, 2020, 268 pp.
Q. Guo, X. L. Si, Y. T. Shi, H. S. Yang, X. Y. Liu, H. Liang, P. F. Tu, and Q. Y. Zhang, J. Nat. Prod., 82, 3288 (2019).
X. Wei, L. P. Jiang, Y. Guo, A. Khan, Y. P. Liu, F. H. Yu, B. Wang, C. F. Ding, P. F. Zhu, Y. Y. Chen, Y. L. Zhao, Y. B. Chen, Y. F. Wang, and X. D. Luo, Nat. Prod. Bioprospect., 7, 413 (2017).
Y. D. Wei, L. H. Yan, H. Liang, M. X. Zhu, D. L. Ye, and Q. Y. Zhang, J. Chin. Pharm. Sci., 24, 169 (2015).
Y. B. Zhang, W. Z. Yang, C. L. Yao, R. H. Feng, M. Yang, and D. A. Guo, Fitoterapia, 96, 39 (2014).
R. Li, J. Cheng, M. Jiao, L. Li, C. Guo, S. Chen, and A. Liu, Fitoterapia, 116, 17 (2017).
B. Ma, S. K. Liu, and Y. Y. Xie, Asian J. Tradit. Med., 4, 85 (2009).
M. C. Deng, W. Jiao, W. W. Dong, C. B. Yang, and R. H. Lu, Nat. Prod. Res. Dev., 21, 242 (2009).
R. X. Li, J. T. Cheng, M. J. Jiao, J. Zhang, S. Chen, C. Guo, and A. Liu, Chin. Tradit. Herb. Drugs, 48, 1499 (2017).
Q. Guo, H. S. Yang, X. Y. Liu, X. L. Si, H. Liang, P. F. Tu, and Q. Y. Zhang, Fitoterapia, 127, 47 (2018).
K. W. Woo, W. S. Suh, L. Subedi, S. Y. Kim, S. U. Choi, K. H. Kim, and K. R. Lee, Heterocycles, 91, 2355 (2015).
T. S. Wu, J. H. Yeh, and P. L. Wu, Phytochemistry, 40, 121 (1995).
H. Naoto, K. Tetsushi, S. Masahiro, and Y. Tomotaka, Mokuzai Gakkaishi, 35, 348 (1989).
Acknowledgment
This research was financially supported by the National Natural Science Foundation of China (NSFC; No. 8187141165) and the Drug Innovation Major Project of China (No. 2018ZX09711001-008-003).
Author information
Authors and Affiliations
Corresponding author
Additional information
Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2022, pp. 863–865.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Liu, XY., Guo, Q., Zhang, YS. et al. Enantiomeric Phenylpropanoids from Uncaria rhynchophylla. Chem Nat Compd 58, 1026–1030 (2022). https://doi.org/10.1007/s10600-022-03860-1
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10600-022-03860-1