Bioactive terpenoids 1 and 2 along with a known compound, β-sitosterol, have been isolated from the DCM extract of the fruits of Lagerstroemia speciosa. Structures of 1 and 2 have been established by spectroscopic analysis. In vitro antibacterial and antifungal activity of 1 and 2 have been reported. Compound 1 showed poor activity, but compound 2 exhibited significant antibacterial and antifungal activities. Molecular docking study of 2 also showed a good docking score within the binding pocket of the selected proteins.
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The authors are thankful to the authority of Chittagong University of Engineering & Technology (CUET) for providing necessary financial support to carry out this research work.
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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2022, pp. 415–419.
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Rabi, S., Islam, M.N., Islam, M.D. et al. Bioactive Terpenoid from the Fruits of Lagerstroemia speciosa and its Molecular Docking Study. Chem Nat Compd 58, 485–490 (2022). https://doi.org/10.1007/s10600-022-03716-8
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DOI: https://doi.org/10.1007/s10600-022-03716-8