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Iridoids and Cytotoxic Terpenes from Lindenbergia indica

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Chemistry of Natural Compounds Aims and scope

A new iridoid aglycone, 1-acetylscyphiphin B2, along with two known iridoid aglycones and three triterpenes, was isolated from the whole plant of Lindenbergia indica. The known compounds were identified as scyphiphin B1, 1β,6β,7α,8α,10-pentahydroxy-cis-2-oxabicyclo[4.3.0]nonane, salacianol, 20-hydroxylupan-3-one, and acetylursolic acid, all of which constitute the first record of such compounds from this species. The isolation of iridoids from this plant supports the taxonomic position within the tribe Gratioleae. Salacianol and acetylursolic acid exhibited moderate cytotoxic activity on all tested stomach cancer cell lines.

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Acknowledgment

We thank Dr. K Miraz Rahman of the School of Cancer and Pharmaceutical Science, King’s College London for providing technical assistance regarding NMR and HR-MS.

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Authors and Affiliations

  1. Department of Pharmacy, University of Asia Pacific, 1205, Dhaka, Bangladesh

    Farina Aziz & Md Abdullah Al Noman

  2. Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka, 1000, Bangladesh

    Choudhury Mahmood Hasan & Monira Ahsan

Authors
  1. Farina Aziz
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  2. Md Abdullah Al Noman
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  3. Choudhury Mahmood Hasan
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  4. Monira Ahsan
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Correspondence to Farina Aziz.

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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2022, pp. 386–389.

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Aziz, F., Al Noman, M.A., Hasan, C.M. et al. Iridoids and Cytotoxic Terpenes from Lindenbergia indica. Chem Nat Compd 58, 450–454 (2022). https://doi.org/10.1007/s10600-022-03706-w

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  • DOI: https://doi.org/10.1007/s10600-022-03706-w

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