Two new anthraquinones, 2,6-dimethyl-3-hydroxy-5-methoxyanthraquinone (1) and 2,5-dimethyl-6-hydroxy-3-methoxyanthraquinone (2), were isolated from the twigs of Cassia alata. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their antibacterial activity. The results showed that both compounds exhibited high antibacterial activity against 11 microbial strains isolated from the saliva of smokers.
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Acknowledgment
This project was supported financially by the Foundation of China Tobacco Company (110201901021 (JY-08)), the Foundation of Yunnan Tobacco Industry Co., Ltd., (No. 2019JC04), the Yunnan Applied Basic Research Projects for Excellent Young Scholars (Grant to M.Z.), and the Yunnan Innovative Research Team (2019HC020).
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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2022, pp. 357–359.
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Yang, WW., Xiao, D., Yin, GY. et al. Two New Antibacterial Anthraquinones from the Twigs of Cassia alata. Chem Nat Compd 58, 414–417 (2022). https://doi.org/10.1007/s10600-022-03696-9
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DOI: https://doi.org/10.1007/s10600-022-03696-9