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Secondary Metabolites and Antifungal Activity of the Endophytic Fungus Streptomyces humidus SCB0232 from Water Chestnut

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Chemistry of Natural Compounds Aims and scope

A new macrolide, named concanamycin H (1), together with 12 known compounds (2–13), was isolated from the endophytic Streptomyces humidus SCB0232 for the first time. Compounds 1–13 were identified by analysis of spectroscopic data. Compounds trienomycin A (2) and trienomycin E (3) exhibited moderate inhibitory activities against Fusarium verticillioides and Phytophthora infestans with IC50 values ranging from 32.64 to 72.35 μg·mL–1.

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Acknowledgment

This research was financially supported by the National Science Foundation of China (31772032), State Key Laboratory of Applied Microbiology of Southern China (SKLAM006-2015), and Scientific Research Projects of Huizhou University (20170406122437260).

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Authors and Affiliations

  1. School of Life Sciences, Huizhou University, 516007, Huizhou, P. R. China

    Zhen-Cheng Lv, Jia-Hui Yan, Yong-Hong Peng & Liang-Xiong Xu

  2. College of Life Sciences, South China Normal University, 510631, Guangzhou, P. R. China

    Xiang-Lu Zhou & Yong-Hong Peng

Authors
  1. Zhen-Cheng Lv
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  2. Xiang-Lu Zhou
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  3. Jia-Hui Yan
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  4. Yong-Hong Peng
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  5. Liang-Xiong Xu
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Corresponding author

Correspondence to Liang-Xiong Xu.

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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2022, pp. 339–341.

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Lv, ZC., Zhou, XL., Yan, JH. et al. Secondary Metabolites and Antifungal Activity of the Endophytic Fungus Streptomyces humidus SCB0232 from Water Chestnut. Chem Nat Compd 58, 390–393 (2022). https://doi.org/10.1007/s10600-022-03689-8

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  • DOI: https://doi.org/10.1007/s10600-022-03689-8

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