Lectin-like proteins (LLP) from Cuscuta europaea parasitizing Alhagi L. were isolated and characterized. They were found to exhibit dose-dependent cytotoxic activity against various passaged cell lines. Combined action of LLP50 and etoposide and colchicine suggested that the LLP50 affected primarily the S-period of cell division.
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References
D. B. Korman, Vopr. Onkol., 6, 689 (2011).
A. Thies, P. Dantel, and A. Meyer, Br. J. Cancer., 98, 106 (2008).
I. Siegle, P. Fritz, and M. Mc Clellan, Anticancer Res., 21, 2687 (2001).
E. Anis, S. Ahmed, G. Mustafa, and Y. Badar, Nat. Prod. Sci., 5, 124 (1999).
Z. D. Zhelev, S. A. Stanilova, and B. G. Carpenter, Biochem. Biophys. Res. Commun., 202, 186 (1994).
K. A. Kakhorova, Z. S. Khashimova, and E. O. Terenteva, Asian J. Pharm. Pharmacol., 4 (3), 265 (2018).
S. V. Pospelov, Khim. Rastit. Syr’ya, 3, 143 (2012).
D. N. Olennikov and L. M. Tankhaeva, Byull. Sib. Med., 2, 118 (2006).
A. A. Romanovskaya and V. N. Nikandrov, Tsitologiya, 49 (8), 656 (2007).
Z. S. Khashimova and K. A. Kakhorova, Uzb. Biol. Zh., 3, 16 (2019).
Z. S. Khashimova, K. A. Kakharova, N. Zh. Sagdnev, F. A. Ibragimov, Yu. V. Beresneva, A. S. Turaev, and Sh. I. Salikhov, UZ Pat. No. IAP 05428 (2017).
K. A. Kakharova, Z. S. Khashimova, and N. Zh. Sagdiev, Evraziiskii Soyuz Uchenykh, 3 (24), 40 (2016).
T. Mosmann, J. Immunol. Methods, 65, 55 (1983).
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Translated from Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2022, pp. 273–275.
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Khashimova, Z.S., Kakhorova, K.A., Ishimov, U.Z. et al. Isolation, Characterization, and Biological Activity of Proteins from Cuscuta europaea. Chem Nat Compd 58, 316–319 (2022). https://doi.org/10.1007/s10600-022-03667-0
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DOI: https://doi.org/10.1007/s10600-022-03667-0