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New Metabolite from the Fungus Monascus argentinensis BCRC 33998

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Chemistry of Natural Compounds Aims and scope

Phytochemical investigation of the CH2Cl2-soluble fraction of the EtOH extract of red mold rice fermented with the white mutant of the fungus Monascus argentinensis BCRC 33998 (Eurotiaceae) led to the isolation and characterization of a new diterpenoid, monascusargentinoic acid (1). The structure of the new compound was elucidated by analysis of its spectroscopic data, including MS, 1D, and 2D NMR experiments, and comparison with literature data of known compounds.

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Acknowledgment

This work was kindly supported by the Food Industry Research and Development Institute and supported by Ministry of Science and Technology, R.O.C. (MOST-108-2320-B-080-002-). The authors thank Senior Technician Mrs. Chyi Jia Wang of the Center for Resources, Research, and Development of Kaohsiung Medical University for measuring the 2D NMR data. They also thank Dr. Ni Ni Naing, Librarian, Universities’ Central Library (UCL) (Lower Myanmar) and Daw May Kha Lwin, Librarian, University of Mandalay Library (Upper Myanmar). We are very grateful to the two teachers for providing valuable academic information.

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Authors and Affiliations

  1. Faculty of Pharmacy, School of Pharmaceutical Sciences, National Yang Ming Chiao Tung University (NYCU), 112, Taipei, Taiwan

    Jih-Jung Chen

  2. Department of Medical Research, China Medical University Hospital, 404, Taichung, Taiwan

    Jih-Jung Chen

  3. Bioresource Collection and Research Center (BCRC), Food Industry Research and Development Institute (FIRDI), 300, Hsinchu, Taiwan

    Ming-Jen Cheng & Ming-Der Wu

  4. College of Oriental Medicine, Rangsit University, Pathum Thani, 12000, Thailand

    Nanthaphong Khamthong

Authors
  1. Jih-Jung Chen
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  2. Ming-Jen Cheng
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  3. Ming-Der Wu
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  4. Nanthaphong Khamthong
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Corresponding author

Correspondence to Ming-Jen Cheng.

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Published in Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2022, pp. 250–251.

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Chen, JJ., Cheng, MJ., Wu, MD. et al. New Metabolite from the Fungus Monascus argentinensis BCRC 33998. Chem Nat Compd 58, 287–289 (2022). https://doi.org/10.1007/s10600-022-03661-6

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  • DOI: https://doi.org/10.1007/s10600-022-03661-6

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