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Zinc-Binding Peptides from Protein of Cicer arietinum

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Chemistry of Natural Compounds Aims and scope

A zinc-binding peptide was obtained from the albumin fraction of chickpea Cicer arietinum by separating Zn2+ using immobilizing metal-affinity chromatography followed by isolation using reversed-phase HPLC. GC-MS results showed that the molecular mass of the peptide was 3896 Da and that the peptide consisted of the 34 amino-acid residues IVQQPDGEKSERKIENENGEGEDGEQDLTVYDFE. This peptide was determined to be a fragment of a protein with a zinc finger.

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Acknowledgment

The work was financed by the Chinese Foundation for Science and Technology Support of Xinjiang-Uyghur Autonomous Region of China (Grant No. 2020E02105), by the Presidential Initiative for International Stipends of the Chinese Academy of Sciences (Grant No. 2021VBA0012), the Stipend Program of the President, CAS-TWAS, PIFI, CAS Foundation Project No. 2019VBA0013, and the Tian-Shan Pine Project for 2020: Candidate Pool of Leading Talent for Scientific and Technical Innovation.

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Correspondence to A. Yili.

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Translated from Khimiya Prirodnykh Soedinenii, No. 1, January–February, 2022, pp. 78–81.

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Mukhamedov, N., Mirzaakhmedov, S.Y., Gao, Y.H. et al. Zinc-Binding Peptides from Protein of Cicer arietinum. Chem Nat Compd 58, 86–89 (2022). https://doi.org/10.1007/s10600-022-03602-3

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  • DOI: https://doi.org/10.1007/s10600-022-03602-3

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