Pleunebron A (1), a new cadinane sesquiterpenoid, together with three known drimane sesquiterpenoids (2–4), was isolated from cultures of the edible mushroom Pleurotus nebrodensis. Their structures were elucidated on the basis of extensive spectroscopic methods. Compounds 1 and 2 were tested for their cytotoxicities against five human cancer cell lines and for their inhibitory activity against isozymes of 11β-hydroxysteroid dehydrogenases (11β-HSD).
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Acknowledgment
This project was supported by the Ningxia Normal University Research Grant (NXSFZDA1904), the First-Rate Discipline (Education) Construction Project of the Higher Education Institutions of Ningxia (NXYLXK2017B110, China, the Natural Science Foundation of Ningxia, China (2019AAC03245), the Key Research Foundation of Ningxia, China (2019BDE03009), the “Domestic Talent 312 Program” of Ningxia, China (NDB2018.139), the Guyuan Science and Technology Support Program (2018GYYQ0007 and 2019GKGY039), the National Natural Science Foundation of China (31760090), the Program for Innovation Talents of Science and Technology in Ningxia, China (KJT2015005), Youth Talent Cultivation Project in Ningxia, China (NXRS2017(279)), the Guyuan Talent Support Program (2019GYSZZB1202), and the Engineering and Technology Research Center of Liupanshan Resources Grant (HGZD20-02), Ningxia Normal University, China.
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Published in Khimiya Prirodnykh Soedinenii, No. 1, January–February, 2022, pp. 37–39.
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Ding, JH., Han, XN., Liu, SW. et al. Sesquiterpenoids from the Edible Mushroom Pleurotus nebrodensis. Chem Nat Compd 58, 37–39 (2022). https://doi.org/10.1007/s10600-022-03592-2
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DOI: https://doi.org/10.1007/s10600-022-03592-2