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Conformational Dynamics and Absolute Configuration of Sawaranin

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Chemistry of Natural Compounds Aims and scope

Butyrolactone 1 was isolated from the EtOAc fraction of the EtOH extract of the aerial part of Geranium charlesii (Aitch. & Hemsl.) Vved. The configurations of all chiral centers of 1 were established by an X-ray crystal structure analysis. The structure of 1 was (3S,4R,5S,6R,7S)-3-p-hydroxyphenyl-5,6,7-trihydroxyoxolan-1,4-olide or the trivial name sawaranin. The dynamics of sawaranin conformers were studied as a function of time in DMSO-d6 solution using NMR spectroscopy and quantum-chemical calculations.

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Authors and Affiliations

  1. S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, Uzbekistan, 100170

    D. R. Siddikov, Kh. M. Bobakulov, K. K. Turgunov, S. Z. Nishanbaev, B. Tashkhodzhaev, I. D. Sham′yanov, V. P. Bruskov & N. D. Abdullaev

  2. Tashkent Institute of Irrigation and Agricultural Mechanization Engineers, 39 Kari Niyazov St., Tashkent, Uzbekistan, 100000

    Kh. M. Bobakulov & S. Z. Nishanbaev

  3. Turin Polytechnic University, Tashkent, Uzbekistan, 100095

    K. K. Turgunov

Authors
  1. D. R. Siddikov
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  2. Kh. M. Bobakulov
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  3. K. K. Turgunov
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  4. S. Z. Nishanbaev
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  5. B. Tashkhodzhaev
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  6. I. D. Sham′yanov
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  7. V. P. Bruskov
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  8. N. D. Abdullaev
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Corresponding author

Correspondence to D. R. Siddikov.

Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2021, pp. 862–865.

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Siddikov, D.R., Bobakulov, K.M., Turgunov, K.K. et al. Conformational Dynamics and Absolute Configuration of Sawaranin. Chem Nat Compd 57, 1005–1009 (2021). https://doi.org/10.1007/s10600-021-03538-0

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  • DOI: https://doi.org/10.1007/s10600-021-03538-0

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