Two new aporphine alkaloids, amocurines D and E (1 and 2), together with five known compounds (3–7), were isolated from the stems of Amoora cucullata. The structures of these compounds were elucidated based on their spectroscopic data. Compound 1 showed significant activities against Staphylococcus aureus (ATCC25923) and Bacillus subtilis (ATCC6633) with MIC value of 3.1 μg/mL, whereas 2 exhibited selective antibacterial activity against B. subtilis.
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Acknowledgment
This research was financially supported by the Prince of Songkla University, Thailand. We are grateful to Assoc. Prof. Dr. Surat Laphookhieo, School of Science, Mae Fah Luang University, for giving valuable suggestions and Assoc. Prof. Dr. Seppo Karrila, Faculty of Science and Industrial Technology, Prince of Songkla University, for helpful comments and suggestions on our draft manuscript.
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Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2021, pp. 775–777.
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Chumkaew, P., Teerapongpisan, P. & Pechwang, J. Two New Aporphine Alkaloids from Amoora cucullata and their Antibacterial Activity. Chem Nat Compd 57, 907–910 (2021). https://doi.org/10.1007/s10600-021-03508-6
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DOI: https://doi.org/10.1007/s10600-021-03508-6