Skip to main content
Log in

Two New Aporphine Alkaloids from Amoora cucullata and their Antibacterial Activity

  • Published:
Chemistry of Natural Compounds Aims and scope

Two new aporphine alkaloids, amocurines D and E (1 and 2), together with five known compounds (3–7), were isolated from the stems of Amoora cucullata. The structures of these compounds were elucidated based on their spectroscopic data. Compound 1 showed significant activities against Staphylococcus aureus (ATCC25923) and Bacillus subtilis (ATCC6633) with MIC value of 3.1 μg/mL, whereas 2 exhibited selective antibacterial activity against B. subtilis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1.

Similar content being viewed by others

References

  1. M. S. Abdelfattah, K. Toume, F. Ahmed, S. K. Sadhu, and M. Ishibashi, Chem. Pharm. Bull., 58, 1116 (2010).

    Article  CAS  Google Scholar 

  2. P. Chumkaew, C. Karalai, C. Ponglimanont, and K. Chantrapromma, J. Nat. Prod., 66, 540 (2003).

    Article  CAS  Google Scholar 

  3. P. Chumkaew, S. Kato, and K. Chantrapromma, J. Asian. Nat. Prod. Res., 12, 424 (2010).

    Article  CAS  Google Scholar 

  4. P. Chumkaew, A. Phatthiya, U. Werapun, and T. Srisawat, Chem. Nat. Compd., 55, 471 (2019).

    Article  CAS  Google Scholar 

  5. P. Chumkaew and T. Srisawat, J. Asian Nat. Prod. Res., 19, 247 (2017).

    Article  CAS  Google Scholar 

  6. P. Chumkaew and T. Srisawat, J. Nat. Med., 73, 273 (2019).

    Article  CAS  Google Scholar 

  7. P. Chumkaew, S. Kato, and K. Chantrapromma, Chem. Pharm. Bull., 54, 1344 (2006).

    Article  CAS  Google Scholar 

  8. P. Chumkaew, P. Teerapongpisan, J. Pechwang, and T. Srisawat, Rec. Nat. Prod., 13, 491 (2019).

    Article  CAS  Google Scholar 

  9. D. D. Thien, T. T. Thuy, N. Q. Huy, H. V. Thuy, L. T. T. Duong, and N. T. Tam, Chem. Nat. Compd., 54, 613 (2018).

    Article  CAS  Google Scholar 

  10. Q. Huang, J. Chen, W. Zhang, B. Zhou, C. Zhang, W. H. Gerwick, and Z. Cao, Phytochemistry, 150, 85 (2018).

    Article  CAS  Google Scholar 

  11. H. N. Lyu, K. W. Zeng, N. K. Cao, M. B. Zhao, Y. Jiang, and P. F. Tu, Phytochemistry, 156, 241 (2018).

    Article  CAS  Google Scholar 

  12. M. S. Atan, K. A. Dzulkefly, S. M. Aspollah, K. Anuar, and S. Vijay, Asia. J. Chem., 23, 3824 (2011).

    CAS  Google Scholar 

  13. S. Zhu, H. Hu, J. Hu, J. Li, F. Hu, and Y. Wang, J. Coord. Chem., 71, 2441 (2018).

    Article  CAS  Google Scholar 

  14. Y. C. Ge, H. J. Zhang, K. W. Wang, and X. F. Fan, Phytochemistry, 154, 73 (2018).

    Article  CAS  Google Scholar 

  15. J. W. Dong, X. J. Li, L. Cai, J. Y. Shi, Y. F. Li, C. Yang, and Z. J. Li, J. Pharm. Biomed. Anal., 160, 330 (2018).

    Article  CAS  Google Scholar 

  16. P. Wafo, B. Nyasse, C. Fontaine, and B. L. Sondengam, Fitoterapia, 70, 157 (1999).

    Article  CAS  Google Scholar 

  17. Y. G. Guo, Y. H. Ding, G. J. Wu, S. L. Zhu, Y. F. Sun, S. K. Yan, F. Qian, H. Z. Jin, and W. D. Zhang, Fitoterapia, 127, 96 (2018).

    Article  CAS  Google Scholar 

Download references

Acknowledgment

This research was financially supported by the Prince of Songkla University, Thailand. We are grateful to Assoc. Prof. Dr. Surat Laphookhieo, School of Science, Mae Fah Luang University, for giving valuable suggestions and Assoc. Prof. Dr. Seppo Karrila, Faculty of Science and Industrial Technology, Prince of Songkla University, for helpful comments and suggestions on our draft manuscript.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Parinuch Chumkaew.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2021, pp. 775–777.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chumkaew, P., Teerapongpisan, P. & Pechwang, J. Two New Aporphine Alkaloids from Amoora cucullata and their Antibacterial Activity. Chem Nat Compd 57, 907–910 (2021). https://doi.org/10.1007/s10600-021-03508-6

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10600-021-03508-6

Keywords

Navigation