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24-Epimarkhacanasin C, An Epimeric Cycloartane-Type Triterpenoid from the Leaves of Markhamia stipulata var. canaense

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Chemistry of Natural Compounds Aims and scope

One new cycloartane-type triterpenoid, named 24-epimarkhacanasin C (1), together with four known flavonoids, apigenin (2), luteolin (3), apigenin 7-O-β-D-glucopyranoside (4), and luteolin 7-O-β-Dglucopyranoside (5), was isolated by various chromatographic methods from the ethyl acetate extract of Markhamia stipulata var. canaense leaves. Their structures were elucidated by IR, UV, HR-ESI-MS, and NMR experiments. All compounds were reported for the first time from this species. Their cytotoxicities were evaluated against human breast cancer cell line (MCF-7) by SRB assay. The isolated compounds 1, 3, and 4 exhibited significant cytotoxic activity (IC50 ranged from 53.38 to 68.32 μg/mL), while compounds 2 and 5 did not show activity.

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References

  1. D. J. Mabberley, Mabberley′s Plant-book: a Portable Dictionary of Plants, Their Classification and Uses, 3rd Edition, Cambridge University Press, New York, 2008.

    Google Scholar 

  2. V. S. Dang, Taiwania, 60 (3), 129 (2015).

    Google Scholar 

  3. T. N. Ngo, N. M. Phan, T. D. Bui, V. S. Dang, C. L. Tran, D. T. Mai, and T. P. Nguyen, Phytochem. Lett., 22, 251 (2017).

    Article  CAS  Google Scholar 

  4. T. N. Ngo, C. T. Vo, N. K. T. Pham, N. M. Phan, T. D. Bui, Q. L. Ngo, V. S. Dang, C. L. Tran, D. T. Mai, and T. P. Nguyen, Nat. Prod. Res., 33 (2), 174 (2019).

    Article  CAS  Google Scholar 

  5. T. N. Ngo, N. D. P. Nguyen, N. T. L. Nguyen, N. K. T. Pham, N. M. Phan, T. D. Bui, Q. L. Ngo, V. S. Dang, C. L. Tran, D. T. Mai, and T. P. Nguyen, Nat. Prod. Res., 34 (13), 1820 (2020).

    Article  CAS  Google Scholar 

  6. D. G. Lee, S. Y. Mok, C. Choi, E. J. Cho, H. Y. Kim, and S. Lee, J. Agric. Chem. Env., 1 (1), 28 (2012).

    Google Scholar 

  7. S. Lee, M. J. Choi, J. M. Choi, S. Lee, H. Y. Kim, and E. J. Cho, J. Med. Plants Res., 6 (40), 5377 (2012).

    Article  CAS  Google Scholar 

  8. M. G. Phan and T. S. Phan, Vietnam J. Chem., 42 (4), 496 (2004).

    CAS  Google Scholar 

  9. M. F. Wang, J. E. Simon, I. F. Avilies, K. He, Q. Y. Zheng, and Y. Tadmor, J. Agric. Food Chem., 51 (3), 601 (2003).

    Article  CAS  Google Scholar 

  10. X. I. Isaev, M. B. Gorovits, N. D. Abdullaev, and N. K. Abubakirov, Chem. Nat. Compd., 20, 691 (1984).

    Article  Google Scholar 

  11. K. J. Kucherbaev, K. K. Uteniyazov, V. V. Kachala, Z. Saatov, and A. S. Shashkov, Chem. Nat. Compd., 38, 175 (2002).

    Article  CAS  Google Scholar 

  12. K. Dzh. Kucherbaev, K. K. Uteniyazov, V. V. Kachala, Z. Saatov, and A. S. Shashkov, Chem. Nat. Compd., 38, 447 (2002).

  13. F. Karabey, I. A. Khan, and E. Bedir, Phytochem. Lett., 5, 320 (2012).

    Article  CAS  Google Scholar 

  14. L. Lu, J. C. Chen, Y. Li, Ch. Qing, Y. Y. Wang, Y. Nian, and M. H. Qiu, Chem. Pharm. Bull., 60 (5), 571 (2012).

    Article  CAS  Google Scholar 

  15. T. Kh. Naubeev, A. A. Zhanibekov, K. K. Uteniyazov, Kh. M. Bobakulov, and N. D. Abdullaev, Chem. Nat. Compd., 49, 1048 (2014).

    Article  CAS  Google Scholar 

  16. T. V. Ganenko, M. I. Isaev, A. S. Gromova, N. D. Abdullaev, V. I. Lutskii, M. F. Larin, A. A. Semenov, M. B. Gorovits, and N. K. Abubakirov, Chem. Nat. Compd., 22, 288 (1986).

    Article  Google Scholar 

  17. X. I. Isaev, B. A. Imomnazarov, Yu. M. Fadeev, and P. A. Kintya, Chem. Nat. Compd., 28, 315 (1992).

    Article  Google Scholar 

  18. F. Ch. Meng, C. Yuan, X. J. Huang, W. J. Wang, L. G. Lin, X. T. Zhang, H. Y. Jiao, and Q. W. Zhang, Phytochem. Lett., 15, 108 (2016).

    Article  CAS  Google Scholar 

  19. B. Aslanipour, D. Gulcemal, A. Nalbantsoy, H. Yusufogl, and E. Bedir, Phytochem. Lett., 21, 66 (2017).

    Article  CAS  Google Scholar 

  20. M. N. T. Nguyen and T. D. Ho-Huynh, BMC Compl. Altern. Med., 16, 220 (2016).

    Article  Google Scholar 

  21. T. P. Nguyen, T. V. H. Le, D. T. Mai, and T. D. Le, Phytochem. Lett., 11, 102 (2015).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, 100000, Vietnam

    Trong Nghia Ngo, Dinh Tri Mai, Cong Luan Tran & Tan Phat Nguyen

  2. Kien Giang University, Kien Giang Province, 920000, Vietnam

    Trong Nghia Ngo

  3. Tan Hiep High School, Kien Giang Province, 920000, Vietnam

    Ngoc Thien Ly Nguyen

  4. Institute of Chemical Technology, Vietnam Academy of Science and Technology, Ho Chi Minh City, 700000, Vietnam

    Nhat Minh Phan, Trong Dat Bui, Dinh Tri Mai & Tan Phat Nguyen

  5. Ho Chi Minh City Institute of Physics, Vietnam Academy of Science and Technology, Ho Chi Minh City, 700000, Vietnam

    Quan Hien Nguyen

  6. School of Education, Can Tho University, Can Tho City, 900000, Vietnam

    Quoc Luan Ngo

  7. Tay Do University, Can Tho City, 900000, Vietnam

    Cong Luan Tran

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  1. Trong Nghia Ngo
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  2. Ngoc Thien Ly Nguyen
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  4. Trong Dat Bui
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  6. Quoc Luan Ngo
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  7. Dinh Tri Mai
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  8. Cong Luan Tran
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  9. Tan Phat Nguyen
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Corresponding author

Correspondence to Tan Phat Nguyen.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2021, pp. 748–750.

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Ngo, T.N., Nguyen, N.T.L., Phan, N.M. et al. 24-Epimarkhacanasin C, An Epimeric Cycloartane-Type Triterpenoid from the Leaves of Markhamia stipulata var. canaense. Chem Nat Compd 57, 875–878 (2021). https://doi.org/10.1007/s10600-021-03501-z

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  • DOI: https://doi.org/10.1007/s10600-021-03501-z

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