Skip to main content
SpringerLink
Log in

A Novel Lactam Metabolite from Penicillium sclerotium D35

  • Published:
Chemistry of Natural Compounds Aims and scope

A novel lactam metabolite, 1-pentyl-8-oxa-3,6-diazabicyclo[3.2.1]octane-2,4,7-trione (1), was isolated from Penicillium sclerotium D35. The structure of the new compound 1 was elucidated by spectroscopic methods, including 1D and 2D NMR data and HR-MS. Compound 1 showed moderate nematode suppression activity with LC50 values of 344.722 mg/L.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. D. Reilly and T. P. Curtin, Biochem. J., 37, 36 (1943).

    Article  CAS  Google Scholar 

  2. T. Maccurin and J. Reilly, Nature, 146, 335 (1940).

    Article  Google Scholar 

  3. E. M. Lucas, M. C. Castro, and J. A. Takahashi, Braz. J. Microbiol., 38, 785 (2007).

    Article  Google Scholar 

  4. E. M. Lucas, Y. Machado, and Ferreira, Trop. J. Pharm. Res., 9, 365 (2010).

    Article  CAS  Google Scholar 

  5. L. Zang, W. Wei, and T. Wang, Nat. Prod. Bioprosp., 2, 117 (2012).

    Article  CAS  Google Scholar 

  6. J. Li, J. Wang, and C. S. Jiang, J. Asian Nat. Prod. Res., 16, 542 (2014).

    Article  CAS  Google Scholar 

  7. T. Liu, S. L. F. Meyer, and D. J. Chitwoo, J. Agric. Food Chem., 15, 3127 (2017).

    Article  Google Scholar 

Download references

Acknowledgment

This work was supported by the National Key R&D Program of China under Grant No. 2017YFD0201102; Beijing Key Laboratory of Green Control of Fruit Tree Diseases and Pests in Northern China under Grant No. BZ0432; the Youth Research Fund of Beijing Academy of Agriculture and Forestry Sciences under Grant No. QNJJ201814; Talent Project of Anhui Provincial Department of Education under Grant No. gxgwfx2018063; and Anhui Natural Science Foundation under Grant No. 1908085MH290.

Author information

Authors and Affiliations

  1. Institute of Plant and Environment Protection, Beijing Academy of Agriculture and Forestry Sciences, 100097, Beijing, P. R. China

    T. Liu, J. Zhao, D. Dan & T. T. Zhang

  2. School of Chemistry and Chemical Engineering, Beijing Institute of Technology, 100081, Beijing, P. R. China

    C. L. Gong & Q. Zhang

  3. College of Life and Health Sciences, Anhui Science and Technology University, 233100, Fengyang, P. R. China

    L. L. Gao

Authors
  1. T. Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. C. L. Gong
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. Zhao
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. D. Dan
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. T. T. Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. L. L. Gao
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Q. Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to L. L. Gao or Q. Zhang.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2021, pp. 359–360.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Liu, T., Gong, C.L., Zhao, J. et al. A Novel Lactam Metabolite from Penicillium sclerotium D35. Chem Nat Compd 57, 420–421 (2021). https://doi.org/10.1007/s10600-021-03378-y

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10600-021-03378-y

Keywords

Search

Navigation