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A New Prenylated Flavanonol from the Roots of Sophora flavescens

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Chemistry of Natural Compounds Aims and scope

A new prenylated flavanonol, (2R,3R)-8-isopentenyl-5-methoxy-7,2′,4′-trihydroxyflavanonol (1) was isolated from the roots of Sophora flavescens. The structure was elucidated on the basis of spectroscopic data. Compound 1 exhibited moderate inhibition towards HeLa, HepG2, and HL-60 tumor cell lines at 14.3, 19.2, 31.5 μg/mL, respectively.

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Acknowledgment

This work was supported by the National Natural Science Foundation of China (NSFC, No. 81860716) and Fundamental Research Funds for the Central Universities (Grant Nos. 31920200030, 31920190096, 31920190004, and 31920200047). Ya-Qing Zhang and Fei Zhao contributed equally to this work.

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Authors and Affiliations

  1. Medical College of Northwest Minzu University, Lanzhou, Gansu, P. R. China

    Ya-Qing Zhang, Fei Zhao, Jian-Xiu Ma, Hong-Yun Gan, Xiao-Feng Xie, Zi-Lin Qiao & Jin Zhao

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  1. Ya-Qing Zhang
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  2. Fei Zhao
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  3. Jian-Xiu Ma
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  4. Hong-Yun Gan
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  5. Xiao-Feng Xie
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  6. Zi-Lin Qiao
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  7. Jin Zhao
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Corresponding author

Correspondence to Jin Zhao.

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Published in Khimiya Prirodnykh Soedinenii, No. 1, January–February, 2021, pp. 21–22.

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Zhang, YQ., Zhao, F., Ma, JX. et al. A New Prenylated Flavanonol from the Roots of Sophora flavescens. Chem Nat Compd 57, 20–22 (2021). https://doi.org/10.1007/s10600-021-03271-8

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  • DOI: https://doi.org/10.1007/s10600-021-03271-8

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