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A New Flavonoid Glycoside from Scutellaria barbata

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Chemistry of Natural Compounds Aims and scope

A new flavonoid glycoside 1, together with nine known compounds, has been isolated from Scutellaria barbata D. Don. The structure of compound 1 was elucidated as acacetin 7-O-β-D-galactopyranosyl(1→2)-β-Dglucopyranoside by spectroscopic data (1D and 2D NMR methods) and chemical evidences. Additionally, compound 1 displayed potent inhibitory activity against α-glucosidase with an IC50 value of 8.9 μM in vitro.

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Acknowledgment

This work was supported by the National Natural Science Foundation of China (No. 31201563).

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Authors and Affiliations

  1. Jiangsu Key Laboratory of Crop Genetics and Physiology/Co-Innovation Center for Modern Production Technology of Grain Crops, Yangzhou University, 225009, Yangzhou, P. R. China

    Yang Liu, Xu-Hua Huang, Jia Chen, Jian-Hua Shao & Chun-Chao Zhao

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  1. Yang Liu
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  2. Xu-Hua Huang
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  3. Jia Chen
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  4. Jian-Hua Shao
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  5. Chun-Chao Zhao
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Correspondence to Chun-Chao Zhao.

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Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2020, pp. 876–877.

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Liu, Y., Huang, XH., Chen, J. et al. A New Flavonoid Glycoside from Scutellaria barbata. Chem Nat Compd 56, 1016–1018 (2020). https://doi.org/10.1007/s10600-020-03217-6

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  • DOI: https://doi.org/10.1007/s10600-020-03217-6

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