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A New Dihydrocoumarin from Ficus sycomorus

Chemistry of Natural Compounds volume 56, pages 1013–1015 (2020)Cite this article

A phytochemical study of the fruits and leaves of Ficus sycomorus L. led to the isolation of a new dihydrocoumarin, 4-carboxylic-4-hydroxy-3,4-dihydrocoumarin (1), together with ten known compounds. Moreover, the different extracts of F. sycomorus were screened for cytotoxic activity using the brine shrimp lethality bioassay. The results revealed that all extracts were virtually nontoxic on the shrimps and showed LC50 values greater than 100 μg/mL.

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ACKNOWLEDGMENT

The authors gratefully acknowledge Prof. Dr. Samir A. Ross (National Center for Natural Products Research, University of Mississippi, University, MS 38677, USA; BioMolecular Sciences, Division of Pharmacognosy, School of Pharmacy, University of Mississippi, University, MS 38677, USA) and Dr. Yoshiaki Takaya (Faculty of Pharmacy, Meijo University, Tempaku, Nagoya 468-8503, Japan) for the NMR measurements.

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Authors and Affiliations

  1. Pharmacognosy Department, Faculty of Pharmacy, Assiut University, Assiut, 71526, Egypt

    Samia M. El-Sayyad, Makboul A. Makboul, Rofida Wahman & Salwa F. Farag

  2. Analytical Research Group, Chair of Urban Water Systems Engineering, Technical University of Munich, Munich, Germany

    Rofida Wahman

  3. Pharmacognosy Department, College of Pharmacy, Taif University, Taif, Saudi Arabia

    Salwa F. Farag

Authors
  1. Samia M. El-Sayyad
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  2. Makboul A. Makboul
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  3. Rofida Wahman
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  4. Salwa F. Farag
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Corresponding author

Correspondence to Salwa F. Farag.

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Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2020, pp. 874–875.

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El-Sayyad, S.M., Makboul, M.A., Wahman, R. et al. A New Dihydrocoumarin from Ficus sycomorus. Chem Nat Compd 56, 1013–1015 (2020). https://doi.org/10.1007/s10600-020-03216-7

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  • DOI: https://doi.org/10.1007/s10600-020-03216-7

Keywords

  • Ficus sycomorus
  • dihydrocoumarin
  • isoquercitrin
  • cinaroside
  • brine shrimp lethality bioassay