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A New Flavonoid Glycoside with α-Glucosidase Inhibitory Activity from Galium Verum

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Chemistry of Natural Compounds Aims and scope

A new flavonoid glycoside, apigenin 7-O-(2,4-di-O-acetyl)-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside (1), was isolated from the 95% EtOH extract of Galium verum L. by repeated column chromatography. Its structure was identified by spectral analyses and chemical methods. In addition, the rat intestinal α-glucosidase inhibitory activity of compound 1 was evaluated in vitro.

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References

  1. Jiangsu New Medical College, Dictionary of Chinese Medicine [in Chinese], Shanghai People′s Publishing House, Shanghai, 1977, 2449 pp.

  2. N. S. Lakic, N. M. Mimica-Dukic, J. M. Isak, and B. N. Bozin, Cent. Eur. J. Biol., 5, 331 (2010).

    Google Scholar 

  3. C. C. Zhao, J. H. Shao, X. Li, X. D. Kang, Y. W. Zhang, D. L. Meng, and N. Li, J. Asian Nat. Prod. Res., 10, 611 (2008).

    Article  CAS  Google Scholar 

  4. C. C. Zhao, J. H. Shao, C. J. Zhao, and X. Li, Chem. Nat. Compd., 47, 545 (2011).

    Article  CAS  Google Scholar 

  5. H. Y. Chen, L. F. Tu, C. R. Xiao, and Y. M. Luo, China J. Chin. Mater. Med., 43, 3694 (2018).

    Google Scholar 

  6. C. S. Hudson and J. K. Dale, J. Am. Chem. Soc., 39, 320 (1917).

    Article  CAS  Google Scholar 

  7. Y. H. Pei, H. M. Hua, Z. L. Li, and G. Chen, Acta Pharm. Sin., 46, 127 (2011).

    Google Scholar 

  8. G. M. Bebault, G. G. S. Dutton, N. A. Funnell, and K. L. Mackie, Carbohydr. Res., 63, 183 (1978).

    Article  CAS  Google Scholar 

  9. Q. Fu, K. Zan, M. B. Zhao, S. X. Zhou, S. P. Shi, Y. Jiang, and P. F. Tu, J. Nat. Prod., 73, 1234 (2010).

    Article  CAS  Google Scholar 

  10. C. C. Zhao, J. Chen, J. H. Shao, J. Shen, X. Q. Xu, K. H. Li, W. Y. Gu, M. Zhao, and J. D. Fan, Holzforschung, 72, 1017 (2018).

    Article  CAS  Google Scholar 

Download references

Acknowledgment

This work was supported by grants from the National Natural Science Foundation of China (No. 31201563) and the open foundation of Green Pesticides and Biotechnology Key Laboratory of Guizhou University of the Ministry of Education (2017GDGP0102/2017GDGP0103). We are also grateful to Prof. Qishi Sun, Shenyang Pharmaceutical University, for the identification of the plant.

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Authors and Affiliations

  1. Jiangsu Key Laboratory of Crop Genetics and Physiology/Co-Innovation Center for Modern Production Technology of Grain Crops, Yangzhou University, 225009, Yangzhou, P. R. China

    Xiao-Hui Zhang, Jie Shen, Chun-Chao Zhao & Jian-Hua Shao

Authors
  1. Xiao-Hui Zhang
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  2. Jie Shen
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  3. Chun-Chao Zhao
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  4. Jian-Hua Shao
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Correspondence to Jian-Hua Shao.

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Published in Khimiya Prirodnykh Soedinenii, No. 1, January–February, 2020, pp. 63–64.

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Zhang, XH., Shen, J., Zhao, CC. et al. A New Flavonoid Glycoside with α-Glucosidase Inhibitory Activity from Galium Verum. Chem Nat Compd 56, 67–69 (2020). https://doi.org/10.1007/s10600-020-02945-z

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  • DOI: https://doi.org/10.1007/s10600-020-02945-z

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