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Aminomethylation of Afromosin, Cladrastin, and Their 2-Methyl Derivatives

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Chemistry of Natural Compounds Aims and scope

Aminomethylation of the natural isoflavones afromosin and cladrastin and their 2-methyl derivatives was studied. Several new Mannich bases of 7-hydroxy-6-methoxyisoflavones were synthesized under Mannich reaction conditions using aminals of secondary amines.

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Authors and Affiliations

  1. National University of Food Technologies, 68 Vladimirskaya St., Kiev, 01601, Ukraine

    S. P. Bondarenko

  2. Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, 1 Murmanskaya St., Kiev, 02094, Ukraine

    G. P. Mrug, K. M. Kondratyuk & M. S. Frasinyuk

Authors
  1. S. P. Bondarenko
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  2. G. P. Mrug
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  3. K. M. Kondratyuk
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  4. M. S. Frasinyuk
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Correspondence to S. P. Bondarenko.

Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2018, pp. 559–563.

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Bondarenko, S.P., Mrug, G.P., Kondratyuk, K.M. et al. Aminomethylation of Afromosin, Cladrastin, and Their 2-Methyl Derivatives. Chem Nat Compd 54, 660–664 (2018). https://doi.org/10.1007/s10600-018-2440-x

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  • DOI: https://doi.org/10.1007/s10600-018-2440-x

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