Chemical Constituents of Xylem of Sophora japonica Roots
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Sophora japonica (Leguminosae), a deciduous tree species, is widely distributed in various areas including China, Korea, Japan, and other countries . The buds, flowers, barks, and leaves of S. japonica have long been used in traditional medicines for treating bleeding hemorrhoids, hematuria, hematemesis, hemorrhinia, uterine or intestinal hemorrhage, leukorrhea, conjunctivitis, pyoderma, arteriosclerosis, hypertension, and dizziness [1, 2]. Previous phytochemical investigations of the leaves, fruits, and barks of S. japonica led to the isolation of steroids, phospholipids, flavonoids, alkaloids, triterpenes, and other phenolic compounds [3, 4, 5, 6, 7, 8]. Some of these chemical constituents have exhibited significant biological properties such as anti-inflammatory , anti-tumor [10, 11], and anti-oxidant activities . However, to date, no study has been carried out to investigate the secondary metabolites from the xylem of S. japonica roots.
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This work was supported financially by the Open Fund of State Key Laboratory of Tree Genetics and Breeding (Chinese Academy of Forestry) (Grant No. TGB2016002), National Natural Science Foundation of China (31260400), the Foundation (No. 2016IM003) of Key Laboratory of Industrial Fermentation Microbiology of Ministry of Education and Tianjin Key Lab of Industrial Microbiology (Tianjin University of Science & Technology), the Scientific and Technical supporting plan programs Foundation of Jiangxi (20151BBF60002), and the Science and Technology Major Project Foundation of Jiangxi Academy of Sciences (2016-YZD1-01).