Chemical Constituents of Viburnum odoratissimum and Their Cytotoxic Activities
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The genus Viburnum, distributed from South America to Southeast Asia, is the second large genus of Caprifoliaceae. There are about 240 species all over the world and about 80 species in China. Forty-three of them are used as folk medicine in China for their biological properties, such as antibacterial, anti-inflammatory, antitussive, and antinociceptive, being traditionally used for the treatment of menstrual, stomach, and kidney cramps [1, 2]. In the course of our investigation on the chemical constituents of Viburnum odoratissimum Ker Gawl. var. awabuki and other traditional Chinese medicines [3, 4, 5, 6, 7], 14 compounds were obtained and identified as β-amyrin (1), α-amyrin (2), stigmasta-4-en-3-one (3), ergosta-4,6,8(14),22-tetraen-3-one (4), olean-12-en-3-one (5), lupeol (6), 3-hydroxyolean-12-en-1-one (7), 3-acetoxyolean-12-en-28-ol (8), 3-acetoxyolean-12-en-28-oic acid (9), 3,28-dihydroxyolean-12-ene (10), 3,28-dihydroxyurs-12-ene (11), 28-hydroxyolean-12-en-3-one (12), trans-p...
This work was supported by the NSFC of China (No. 31171701) and Zhejiang Provincial Collaborative Innovation Center of Food Safety and Nutrition (No. 2017SICR110).
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