Antibacterial Indole Alkaloids and Anthraquinones from a Sewage-Derived Fungus Eurotium sp.
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Eurotium, a common fungus closely related to human life, is adapted to high osmotic pressure and can adapt to a low water environment . They are dominant microorganisms that are found during the molding process in the manufacture of Japanese Katsuobushi  and Chinese Fuzhuan brick-tea . Eurotium sp. are a rich source of bioactive secondary metabolites, such as anthraquinones, benzaldehydes, and diketopiperazines . Some of these metabolites possess antimicrobial , antitumor , anti-inflammatory , and cytotoxic activities , as well as antioxidant properties , and the ability to degrade pesticide residues , among others. Therefore, a comprehensive understanding of the characteristics and secondary metabolites of Eurotium would lay a foundation for the reasonable utilization of its resources. Herein, we report the isolation, structural characterization, and biological activities of these compounds.
On the basis of spectral data and by comparison with those...
This work was supported by the Natural Science Foundation of Hebei Province of China (No. B2017201059) and the National Natural Science Foundation of China (No. 41606174). Financial support from Hebei University is acknowledged. We thank Renee Mosi, PhD, from Liwen Bianji, Edanz Group China (www.liwenbianji.cn/ac), for editing the English text of a draft of this manuscript.
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