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Chemistry of Natural Compounds

, Volume 54, Issue 2, pp 396–398 | Cite as

Chemical Constituents of the Fungus Mycoleptodiscus sp. 09F0149

  • Hsun-Shuo Chang
  • Yi-Shuan Chen
  • Ming-Jen Cheng
  • Ho-Cheng Wu
  • Hing-Yuen Chan
  • Sung-Yuan Hsieh
  • Shuen-Shin Yang
  • Ih-Sheng Chen
  • Jih-Jung Chen
Article
  • 29 Downloads

During a program of investigation on potentially bioactive secondary metabolites from Formosan endemic plant endophytes, an endophytic fungal strain, Mycoleptodiscus sp. (Magnaporthaceae) BCRC 09F0149, was isolated from the root of Piper sintenense Hatus. (Piperaceae). Previous chemical investigations of the genus Mycoleptodiscus have received less attention, and only a few articles have been reported [1, 2, 3]. In the course of our search for potentially diverse secondary metabolites from natural fungal sources, we have investigated the minor metabolites of the genus Mycoleptodiscus and examined the EtOAc-soluble fraction of Mycoleptodiscussp. Current phytochemical investigation of the above-mentioned fungus has led to the isolation of seven metabolites, including two known aliphatics, one benzenoid, and four known steroids. The structures of the isolated metabolites were determined by extensive analysis of their spectroscopic data as well as by comparison with literature reports....

Notes

Acknowledgment

This investigation was supported by a grant from the Ministry of Economic Affairs of the Republic of China. The authors also thank Senior Technician Mrs. Chyi-Jia Wang of the Center for Resources, Research and Development (CRRD) of Kaohsiung Medical University for measuring the 2D NMR data.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Hsun-Shuo Chang
    • 1
    • 2
  • Yi-Shuan Chen
    • 2
  • Ming-Jen Cheng
    • 3
  • Ho-Cheng Wu
    • 2
  • Hing-Yuen Chan
    • 3
  • Sung-Yuan Hsieh
    • 3
  • Shuen-Shin Yang
    • 1
  • Ih-Sheng Chen
    • 1
    • 2
  • Jih-Jung Chen
    • 4
    • 5
  1. 1.School of Pharmacy, College of PharmacyKaohsiung Medical UniversityKaohsiungP. R. China
  2. 2.Graduate Institute of Natural Products, College of PharmacyKaohsiung Medical UniversityKaohsiungP. R. China
  3. 3.Bioresource Collection and Research Center (BCRC)Food Industry Research and Development Institute (FIRDI)HsinchuP. R. China
  4. 4.Faculty of Pharmacy, School of Pharmaceutical SciencesNational Yang-Ming UniversityTaipeiP. R. China
  5. 5.Department of Medical ResearchChina Medical University HospitalTaichungP. R. China

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