Chemistry of Natural Compounds

, Volume 54, Issue 2, pp 390–392 | Cite as

Secondary Metabolites of Mycena dendrobii, a Fungus Stimulating the Germination of Gastrodia elata

  • X. X. Liang
  • Y. Pan
  • Q. J. Fan

In recent years, secondary metabolites obtained from fungi have gained considerable attention, as many of them are structurally unique and possess interesting biological and pharmacological properties [1, 2], which prompted us to carry out secondary metabolite studies on the fungus.

Mycena dendrobii is a kind of fungus that provides nutrients to Gastrodia elata in the germination stage [3, 4, 5, 6, 7] and the following growth process [8] by its hyphae. However, the material basis of the germination and growth process of G. elata has not been clarified. In 2000, a preliminary constituents analysis of M. dendrobii was reported [9, 10]. In our early study [11] the primary metabolites of M. dendrobii were reported. In this article we focused on its secondary metabolites, which resulted in six compounds (1–6).

The inoculum of M. dendrobii, identified by Q. J. Fan (Sichuan Agricultural University, Sichuan, China), was collected from Xiaocaoba, Yunnan, China. After fermentation in liquid...



The authors greatly appreciate financial support from the National Natural Science Foundation of China (No. 81703387).


  1. 1.
    F. Zhou, H. C. Zhang, R. Liu, and D. X. Zhang, Chem. Nat. Compd., 49, 568 (2013).CrossRefGoogle Scholar
  2. 2.
    X. C. Liu, H. Li, F. Zhou, and R. M. Wang, Chem. Nat. Compd., 51, 1199 (2015).CrossRefGoogle Scholar
  3. 3.
    S. X. Guo, L. Fan, W. Q. Cao, and X. M. Chen, Mycosystema, 18 (2), 141 (1999).Google Scholar
  4. 4.
    J. T. Xu, S. X. Guo, L. Fan, and R. Na, Mycosystema, 20 (1), 137 (2001).Google Scholar
  5. 5.
    S. X. Guo and Q. Y. Wang, Mycosystema, 20 (3), 408 (2001).Google Scholar
  6. 6.
    H. X. Liu, Y. B. Luo, and H. Liu, Bot. Rev., 76, 241 (2010).CrossRefGoogle Scholar
  7. 7.
    T. Liu, C. M. Li, Y. L. Han, T. Y. Chiang, Y. C. Chiang, and H. M. Sung, BMC Genomics, 16, 185 (2015).CrossRefPubMedPubMedCentralGoogle Scholar
  8. 8.
    L. Fan, S. X. Guo, and J. T. Xu, Mycosystema, 18 (2), 219 (1999).Google Scholar
  9. 9.
    S. X. Guo, X. M. Chen, J. S. Yang, W. Q. Cao, and S. Y. Xiao, Chin. Pharm. J., 35 (6), 372 (2000).Google Scholar
  10. 10.
    X. M. Chen, J. S. Yang, and S. X. Guo, Acta Pharm. Sin., 35 (5), 367 (2000).Google Scholar
  11. 11.
    X. X. Pan, X. X. Liang, and Q. J. Fan, Sydowia, 67, 127 (2015).Google Scholar
  12. 12.
    J. T. Xu, S. X. Guo, L. Fan, and R. Na, Mycosystema, 20 (1), 137 (2001).Google Scholar
  13. 13.
    K. Gao and Z. J. Jia, J. Lanzhou Univ. (Nat. Sci.), 33 (4), 77 (1997).Google Scholar
  14. 14.
    M. Wang, H. Zhou, M. Wirz, Y. Tang, and C. N. Boddy, Biochemistry, 48, 6288 (2009).CrossRefPubMedPubMedCentralGoogle Scholar
  15. 15.
    T. Iwasaki, Y. Megawa, Y. Hayashi, T. Ohshima, and K. Mashima, J. Org. Chem., 73, 5147 (2008).CrossRefPubMedGoogle Scholar
  16. 16.
    M. Zhang, M. Chen, H. Q. Zhang, and S. Sun, Nat. Prod. Res. Dev., 22, 416 (2010).Google Scholar
  17. 17.
    P. Basnet, S. Kadota, S. Terashima, M. Shimizu, and T. Namba, Chem. Pharm. Bull., 41 (7), 1238 (1993).CrossRefPubMedGoogle Scholar
  18. 18.
    C. M. Monteiro, N. M. T. Lourenco, and C. A. M. Afonso, Tetrahedron: Asymmetry, 21, 952 (2010).CrossRefGoogle Scholar
  19. 19.
    T. Fortunati, M. D Acunto, T. Caruso, and A. Spinella, Tetrahedron, 71, 2357 (2015).CrossRefGoogle Scholar
  20. 20.
    M. A. W. Lamers Yvonne, Ghena Rusu, B. P. A. Wijnberg Joannes, and Aede de Groot, Tetrahedron, 59 (47), 9361 (2003).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Natural Medicine Research Center, College of Veterinary MedicineSichuan Agricultural UniversityChengduP. R. China

Personalised recommendations