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Chemistry of Natural Compounds

, Volume 54, Issue 2, pp 350–353 | Cite as

Bioactive Flavonoid Derivatives from Scutellaria luzonica

  • Meng Bai
  • Cai-Juan Zheng
  • Li-Jun Wu
  • Shou-Yuan Wu
  • Yue Cai
  • Guang-Ying Chen
  • Chang-Ri Han
  • Xiao-Ping Song
Article
  • 47 Downloads

Scutellaria is one of the most widely used traditional Chinese herbal medicines, and the other name is “HuangQin” in Chinese [1]. Its root is the traditional medicinal part and has been listed in the Chinese Pharmacopoeia for a long time [2]. The aerial parts of Scutellaria also have diverse and strong therapeutic functions and potentially beneficial effects, such as cardiovascular [3], neuroprotective [4], antitubercular [5], memory improving [6], antitumor [7], and antibacterial activity [8]. There have been previous investigations on the chemical constituents of the roots of Scutellaria luzonica Rolfe, and 18 flavonoids, including 13 flavones, two flavanones, one chalcone, and one flavone glycoside, were isolated from this plant [9]. However, Scutellaria luzonica is a variant of Scutellaria luzonica, and the chemical constituents and bioactivities of S. luzonica have not been reported. In order to search for the bioactive chemical constituents of S. luzonica, 14 flavonoid...

Notes

Acknowledgment

We acknowledge funding from the International S&T cooperation Program of China (ISTCP) (2014DFA40850), Hainan province Natural Science Foundation of innovative research team project (2016CXTD007), Hainan special project for TCM modernization (2015ZY19), and the National Natural Science Foundation of China (21362009 and 81360478).

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Meng Bai
    • 1
  • Cai-Juan Zheng
    • 1
  • Li-Jun Wu
    • 1
  • Shou-Yuan Wu
    • 1
  • Yue Cai
    • 1
  • Guang-Ying Chen
    • 1
  • Chang-Ri Han
    • 1
  • Xiao-Ping Song
    • 1
  1. 1.Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical EngineeringHainan Normal UniversityHaikouP. R. China

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