Lawsonol, a New Bioactive Naphthoquinone Dimer From the Leaves of Lawsonia alba

  • Shammi Akhter
  • Satyajit Roy Rony
  • Muhammad Abdullah Al-Mansur
  • Choudhury Mahmood Hasan
  • Khondaker Miraz Rahman
  • Md. Hossain Sohrab
Article
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A new bioactive naphthoquinone dimer, lawsonol[2-(1,4-dioxo-1,4-dihydronaphthalen-2-yloxy)-3-hydroxynaphthalene-1,4-dione] (1), was isolated from the leaves of Lawsonia alba. Its structure was established on the basis of spectral data, including 2D NMR and HR-MS. Compound 1 exhibited in vitro antibacterial activity against Bacillus megaterium, Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa.

Keywords

Lawsonia alba Lythraceae lawsonol antibacterial activity 

Notes

Acknowledgment

We would like to thank the Bangladesh Council of Scientific and Industrial Research (BCSIR) for providing laboratory facilities.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Shammi Akhter
    • 1
    • 2
  • Satyajit Roy Rony
    • 1
  • Muhammad Abdullah Al-Mansur
    • 3
  • Choudhury Mahmood Hasan
    • 4
  • Khondaker Miraz Rahman
    • 5
  • Md. Hossain Sohrab
    • 1
  1. 1.Pharmaceutical Sciences Research Division, BCSIR Laboratories DhakaDhakaBangladesh
  2. 2.Department of PharmacyUniversity of Asia PacificDhakaBangladesh
  3. 3.Institute of National Analytical Research and Service, BCSIR Laboratories DhakaDhakaBangladesh
  4. 4.Manarat International UniversityDhakaBangladesh
  5. 5.King’s College London, Institute of Pharmaceutical Science, Britannia HouseLondonUK

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