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A New Sydonic Acid Derivative From a Marine Derived-Fungus Aspergillus sydowii

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Chemistry of Natural Compounds Aims and scope

Methyl (3-hydroxy-4-(2-hydroxy-6-methylheptan-2-yl)benzoyl)glycinate (1), a new sydonic acid derivative with glycinate, together with sydonic acid (2), sydowic acid (3), and 7-deoxy-7,14-didehydrosydonic acid (4), were isolated from a marine-derived Aspergillus sydowii strain CUGB-F126. Their structures were elucidated by spectroscopic analysis, including high-resolution mass spectroscopy, and 1D and 2D NMR techniques. All of these compounds did not show inhibitory activity against Staphylococcus aureus and Candida albicans.

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Acknowledgment

This work was supported by the Fundamental Research Funds for the Central Universities (2-9-2015-165) and key lab of marine bioactive substance and modern analytical technique, SOA (MBSMAT-2016-04).

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Authors and Affiliations

  1. School of Ocean Sciences, China University of Geosciences, 100083, Beijing, P. R. China

    Xiuli Xu, Liyuan Yin, Ying Yu, Zhengkun Chen, Huihui Shen & Li Zhou

  2. School of Marine Science and Technology, Zhejiang Ocean University, 316022, Zhoushan, P. R. China

    Shujiang Zhao

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  1. Xiuli Xu
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  2. Shujiang Zhao
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  3. Liyuan Yin
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  4. Ying Yu
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  5. Zhengkun Chen
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  7. Li Zhou
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Correspondence to Xiuli Xu.

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Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2017, pp. 898–899.

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Xu, X., Zhao, S., Yin, L. et al. A New Sydonic Acid Derivative From a Marine Derived-Fungus Aspergillus sydowii . Chem Nat Compd 53, 1056–1058 (2017). https://doi.org/10.1007/s10600-017-2200-3

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  • DOI: https://doi.org/10.1007/s10600-017-2200-3

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