Skip to main content
SpringerLink
Log in

A New Alkaloid with Tracheal Relaxant Effect from the Bulbs of Fritillaria pallidiflora

  • Published:
Chemistry of Natural Compounds Aims and scope

A new isosteroidal alkaloid, yibeinone E (1), along with five known ones, zhebeinone 3-O-β-D-glucoside (2), sinpeinine A (3), yubeinine (4), ebeinone (5), and delavinone (6), were isolated from the bulbs of Fritillaria pallidiflora. Their structures were confirmed on the basis of extensive spectroscopic analysis or comparison with the data in the literature (known compounds). Compound 3 showed an apparent relaxation effect on isolated tracheas.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.
Fig. 2.

Similar content being viewed by others

References

  1. P. Li, H. Ji, G. J. Xu, and L. S. Xu, J. Chin. Pharm. Univ., 24, 360 (1993).

    CAS  Google Scholar 

  2. J. L. Zhou, G. Z. Xin, Z. Q. Shi, M. T. Ren, L. W. Qi, H. J. Li, and P. Li, J. Chromatogr. A, 1217, 7109 (2010).

    Article  CAS  PubMed  Google Scholar 

  3. J. X. Zhang, A. N. Lao, and R. S. Xu, Acta Bot. Sin., 35, 963 (1993).

    CAS  Google Scholar 

  4. Q. H. Liu, X. G. Jia, Y. F. Ren, Muhatal, and X. T. Liang, Acta Pharm. Sin., 19, 894 (1984).

  5. J. Z. Wu, X. P. Pan, M. G. Lou, X. S. Wang, and D. K. Lin, Acta Pharm. Sin., 24, 600 (1989).

    CAS  Google Scholar 

  6. K. Kaneko, T. Katsuhara, and H. Mitsuhashi, Chem. Pharm. Bull., 33, 2614 (1985).

    Article  CAS  Google Scholar 

  7. G. Lin, Y. P. Ho, P. Li, and X. G. Li, J. Nat. Prod., 58, 1662 (1995).

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgment

Financial support of this research was provided by the Program for the National Natural Science Foundation of China (No. U1403201). We thank the Central Asian Drug Discovery and Development Center of the Chinese Academy of Sciences for support of our research, and the Center for Pharmacological Evaluation & Research of SIPI in China for the tracheal relaxant effect experiments.

Author information

Authors and Affiliations

  1. Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics & Chemistry, Chinese Academy of Sciences, Beijing South Road 40-1,Urumqi, 830011, Xinjiang, P. R. China

    Yan Li, A. Yili & H. A. Aisa

  2. Key Laboratory of Xinjiang Indigenous Medicinal Plant Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, 100039, Beijing, P. R. China

    A. Yili, Aziz Muhamat & H. A. Aisa

  3. University of Chinese Academy of Sciences, 100039, Beijing, P. R. China

    Yan Li & Aziz Muhamat

Authors
  1. Yan Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. Yili
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Aziz Muhamat
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. H. A. Aisa
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to H. A. Aisa.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2017, pp. 789–791.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Li, Y., Yili, A., Muhamat, A. et al. A New Alkaloid with Tracheal Relaxant Effect from the Bulbs of Fritillaria pallidiflora . Chem Nat Compd 53, 926–928 (2017). https://doi.org/10.1007/s10600-017-2156-3

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10600-017-2156-3

Keywords

Search

Navigation