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A New Dihydroisocoumarin Derivative from the Extract of the Fungus Monascus-Fermented Rice

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Chemistry of Natural Compounds Aims and scope

Examination of the EtOAc-soluble fraction from a 70% ethanolic extract of red yeast rice fermented with the yellow mutant of the fungus Monascus sp. (Eurotiaceae) yielded a new dihydroisocoumarin derivative, monascusmellein (1). The structure of compound 1 was determined by spectroscopic methods, including UV, IR, HR-ESI-MS, and extensive 1D and 2D NMR analysis.

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References

  1. R. E. Mudgett, Monascus, in: Natural Food Colorants, Science and Technology, G. J. Lauro, F. J. Francis (eds.), Marcel Dekker, New York, 2000, p. 31.

    Google Scholar 

  2. J. Ma, Y. Li, Q. Ye, J. Li, Y. Hua, D. Ju, D. Zhang, R. Cooper, and M. Chang, J. Agric. Food Chem., 48, 5220 (2000).

    Article  CAS  PubMed  Google Scholar 

  3. H. C. Wong and P. E. Koehler, J. Food Sci., 46, 589 (1981).

    Article  CAS  Google Scholar 

  4. Y. C. Su, J. J. Wang, T. T. Lin, and T. M. Pan, J. Ind. Microbiol. Biotechnol., 30, 40 (2003).

    Article  Google Scholar 

  5. P. J. Blanc, M. O. Loret, A. L. Santerre, A. Pareilleux, D. Prome, J. C. Prome, J. P. Laussac, and G. Goma, J. Food Sci., 59, 862 (1994).

    Article  CAS  Google Scholar 

  6. Y. Aniya, I. I. Ohtani, T. Higa, C. Miyagi, H. Gibo, M. Shimabukuro, H. Nakanish, and J. Taira, Free Radical Biol. Med., 286, 999 (1999).

    Google Scholar 

  7. G. F. Wu and X. C. Wu, Acta Microbiol. Sin., 40, 394 (2000).

    CAS  Google Scholar 

  8. P. J. Blanc, M. O. Loret, and G. Goma, Biotechnol. Lett., 17, 291 (1995).

    Article  CAS  Google Scholar 

  9. Y. Kohama, S. Matsumoto, T. Mimura, N. Tanabe, A. Inada, and T. Nakanishi, Chem. Pharm. Bull., 35, 2484 (1987).

    Article  CAS  PubMed  Google Scholar 

  10. P. J. Blanc, M. O. Loret, and G. Goma, Biotechnol. Lett., 17, 291 (1995).

    Article  CAS  Google Scholar 

  11. K. Tsuji, T. Ichikawa, N. Tanabe, S. Abe, S. Tarui, and Y. Nakagawa, Nippon. Nogeikagaku Kaishi, 66, 1241 (1992).

    Article  Google Scholar 

  12. A. Endo, J. Med. Chem., 28, 401 (1985).

    Article  CAS  PubMed  Google Scholar 

  13. L. Martinokova, P. Juzlova, and D. Vesely, J. Appl. Bacteriol., 79, 609 (1995).

    Article  Google Scholar 

  14. H. C. Wong and Y. S. Bau, Plant Physiol., 60, 578 (1977).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. T. Akihisa, H. Tokuda, K. Yasukawa, M. Ukiya, A. Kiyota, N. Sakamoto, T. Suzuki, N. Tanabe, and H. Nishino, J. Agric. Food Chem., 53, 562 (2005).

    Article  CAS  PubMed  Google Scholar 

  16. M. J. Cheng, M. D. Wu, I. S. Chen, and G. F. Yuan, Chem. Pharm. Bull., 56, 394 (2008).

    Article  CAS  PubMed  Google Scholar 

  17. Y. Tanabe, T. Matsumoto, T. Hosoya, H. Sato, and H. Shigemori, Heterocycles, 87, 1481 (2013).

    Article  CAS  Google Scholar 

  18. Y. M. Bi, X. B. Bi, Q. R. Zhao, Y. T. Chen, and J. L. Xie, Helv. Chim. Acta, 87, 2890 (2004).

    Article  CAS  Google Scholar 

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Acknowledgment

This investigation was supported by a grant from the Ministry of Economic Affairs of the Republic of China.

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Authors and Affiliations

  1. Bioresource Collection and Research Center (BCRC), Food Industry Research and Development Institute (FIRDI), 300, Hsinchu, Taiwan

    Ming-Jen Cheng, Hing-Yuen Chan, Ming-Der Wu & Gwo-Fang Yuan

  2. Natural Chemical Ind. Co. Ltd., 500, Changhua, Taiwan

    Yen-Chen Cheng

  3. Faculty of Pharmacy, School of Pharmaceutical Sciences, National Yang-Ming University, 112, Taipei, Taiwan

    Jih-Jung Chen

  4. Department of Medical Research, China Medical University Hospital, 404, Taichung, Taiwan

    Jih-Jung Chen

  5. Research Center for Environmental Medicine, Kaohsiung Medical University, 807, Kaohsiung, Taiwan

    Yu-Ming Hsu

  6. Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, 807, Kaohsiung, Taiwan

    Ih-Sheng Chen

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  1. Ming-Jen Cheng
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  2. Hing-Yuen Chan
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  3. Ming-Der Wu
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  5. Jih-Jung Chen
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  6. Yu-Ming Hsu
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  7. Ih-Sheng Chen
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  8. Gwo-Fang Yuan
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Corresponding authors

Correspondence to Ming-Jen Cheng or Jih-Jung Chen.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2017, pp. 730–732.

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Cheng, MJ., Chan, HY., Wu, MD. et al. A New Dihydroisocoumarin Derivative from the Extract of the Fungus Monascus-Fermented Rice. Chem Nat Compd 53, 856–859 (2017). https://doi.org/10.1007/s10600-017-2140-y

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  • DOI: https://doi.org/10.1007/s10600-017-2140-y

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