The aerial part of the plant Scutellaria intermedia Popov yielded five glucuronides, three of which were identified as chrysin 7-O-β-D-glucuronide, wogonin 7-O-β-D-glucuronide, and baicalein 7-O-β-Dglucuronide (baicalin). IR, UV, PMR, and 13C NMR spectral data and acid hydrolysis of the two new glucuronides established their structures as 5,7,2′-trihydroxyflavone 2′-O-β-D-glucuronopyranoside (4) and scutevulin 2′-O-β-D-glucuronopyranoside (5).
Similar content being viewed by others
References
X. Shang, X. He, X. He, M. Li, R. Zhang, P. Fan, Q. Zhang, and Z. Jia, J. Ethnopharmacol., 128, 279 (2010).
Plant Resources of the USSR. Flowering Plants, Their Chemical Composition, Use. Families Hippuridaceae-Lobeliacae, Nauka, St. Petersburg, 1991, p. 85.
I. I. Chemesova, Rastit. Resur., 29 (2), 89 (1993).
N. Z. Mamadalieva, F. Herrmann, M. Z. El-Readi, A. Tahrani, R. Hamoud, D. R. Egamberdieva, Sh. S. Azimova, and M. Wink, J. Pharm. Pharmacol., 63, 1346 (2011).
V. M. Malikov and M. P. Yuldashev, Chem. Nat. Compd., 38, 357, 473 (2002).
D. N. Olennikov, N. K. Chirikova, and L. M. Tankhaeva, Khim. Rastit. Syr’ya, No. 4, 89 (2009).
A. M. Karimov and E. Kh. Botirov, Khim. Rastit. Syr’ya, No. 1, 5 (2016).
P. Parajuli, N. Joshee, A. Rimando, S. Mittal, and A. K. Yadav, Planta Med., 75, 41 (2009).
Z. Gao, K. Huang, X. Yang, and H. Xu, Biochim. Biophys. Acta, 1472 (3), 643 (1999).
H. G. Park, S. Y. Yoon, J. Y. Choi, G. S. Lee, J. H. Choi, C. Y. Shin, K. H. Son, Y. S. Lee, W. K. Kim, J. H. Ryu, K. H. Ko, and J. H. Cheong, Eur. J. Pharmacol., 574, 112 (2007).
Flora of Uzbekistan [in Russian], Vol. 5, Izd. Akad. Nauk UzSSR, Tashkent, 1961, p. 270.
A. M. Karimov, T. N. Slobodyanyuk, and E. Kh. Botirov, Chem. Nat. Compd., 745 (2017).
T. P. Popova, V. I. Litvinenko, V. G. Gordienko, and D. A. Pakaln, Chem. Nat. Compd., 12, 656 (1976).
G. Bhat, B. A. Ganai, and A. S. Shawl, Nat. Prod. Res., 28 (20), 1685 (2014).
Y. Miyaichi, E. Hanamitsu, H. Kizu, and T. Tomimori, Chem. Pharm. Bull., 54, 435 (2006).
T. Tomimori, Y. Imoto, and Y. Miyaichi, Chem. Pharm. Bull., 38, 3488 (1990).
Y. Kikuchi, Y. Miyaichi, Y. Yamaguchi, H. Kizu, and T. Tomimori, Chem. Pharm. Bull., 39, 1047 (1991).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2017, pp. 543–546.
Rights and permissions
About this article
Cite this article
Karimov, A.M., Slobodyanyuk, T.N. & Botirov, E.K. New Flavonoid Glucuronides from the Aerial Part of Scutellaria intermedia . Chem Nat Compd 53, 638–641 (2017). https://doi.org/10.1007/s10600-017-2079-z
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10600-017-2079-z