Bioactivity-guided fractionation of the EtOAc-soluble fraction of the total ethanolic extract resulted in the isolation and identification of two new resveratrol trimers, rockiol A (1) and rockiol B (2). The relative configurations of these compounds were elucidated mainly by comprehensive 1D and 2D NMR experiments. The two isolated compounds exhibited strong antibacterial activities against Gram-positive bacteria.
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References
J. C. Qi, H. M. Zhou, J. Q. Ma, and P. Li, Cereals Oils, 19, 22 (2005).
S. D. Sarker, P. Whiting, L. Dinan, V. Sil, and H. H. Rees, Tetrahedron, 55, 513 (1999).
C. N. He, Y. C. Zhang, Y. Peng, J. S. Yang, and P. G. Xiao, Phytochem. Lett., 5, 128 (2012).
J. P. Yi, W. X. Zhu, H. L. Ma, and Y. F. Wang, Nat. Prod. Res. Dev., 20, 604 (2009).
S. H. Wu, D. G. Wu, and Y. W. Chen, Chem. Biodiv., 7, 90 (2010).
P. Liu, Y. Q. Niu, R. X. Deng, Z. Y. Lu, X. Liu, and W. P. Yin, Chin. Pharm. J., 49, 1018 (2014).
P. Liu, Y. R. Wang, J. Y. Gao, Z. Y. Lu, W. P. Yin, and R. X. Deng, Molecules, 19, 19459 (2014).
K. X. Yan, K. Terashima, Y. Takaya, and M. Niwa, Tetrahedron, 58, 6931 (2002).
N. Pavel, P. Kloucek, J. Rondevaldova, J. Havlik, L. Kourimska, and L. Kokoska, Fitoterapia, 94, 102 (2014).
C. Kajal, A. P. Lipton, R. P. Raj, and K. K. Vijayan, Food Chem., 119, 1399 (2010).
Acknowledgment
This work was supported by the National Natural Science Foundation of China (No. U1404831), the funds from Henan University of Science and Technology (Nos. ZCX005, CXJJ-Z024), and the fund High-Tech R&D Program Grant from the Henan government of the People’s Republic of China (No. 152102110079).
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Published in Khimiya Prirodnykh Soedinenii, No. 1, January–February, 2017, pp. 44–47.
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Liu, P., Li, XF., Gao, JY. et al. Two New Resveratrol Trimers with Antibacterial Activities from Seed Cake of Paeonia rockii . Chem Nat Compd 53, 51–55 (2017). https://doi.org/10.1007/s10600-017-1909-3
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DOI: https://doi.org/10.1007/s10600-017-1909-3