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Triterpenoids from the Roots and Stems of Rubus alceaefolius

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Chemistry of Natural Compounds Aims and scope

A phytochemical investigation of the roots and stems of Rubus alceaefolius Poir. let to the isolation of two oleanane-type triterpenoids, 2α,3α-dihydroxyolean-11,13(18)-dien-19β,28-olide ( 1 ) and 2α,3α-dihydroxyolean-13(18)-en-28-oic acid ( 2 ), and a unique octanordammarane triterpenoid, 3β-hydroxy- 20,21,22,23,24,25,26,27-octanordammaran-17β-ol ( 3 ), which the current study is the second report of this type of dammarane triterpenoid. Their structures were elucidated on the basis of spectroscopic evidence, including 1D and 2D NMR and IR analysis, and by comparison with literature data. Compounds 1 and 3 are new compounds, and compound 2 is obtained from nature for the first time.

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Acknowledgment

This article is supported by the Science and Technology Foundation of Traditional Chinese Medicine Bureau of Guangdong Province (No. 20111083) and Zhongshan Science and Technology Foundation (No. 20113A007).

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Authors and Affiliations

  1. School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, 510006, Guangzhou, P. R. China

    Pan Chen, Hanjing Yan, Yanfen Chen, Xilong Wang & Lu Ming

  2. Zhongshan Hospital, Guangzhou University of Traditional Chinese Medicine, 528400, Zhongshan, P. R. China

    Quanxi Mei

  3. Zhongshan Campus, Guangdong Pharmaceutical University, 528458, Zhongshan, P. R. China

    Zhijian Fang

Authors
  1. Pan Chen
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  2. Hanjing Yan
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  3. Quanxi Mei
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  4. Yanfen Chen
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  5. Xilong Wang
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  6. Lu Ming
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  7. Zhijian Fang
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Corresponding author

Correspondence to Zhijian Fang.

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Published in Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2016, pp. 218–221.

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Chen, P., Yan, H., Mei, Q. et al. Triterpenoids from the Roots and Stems of Rubus alceaefolius . Chem Nat Compd 52, 248–251 (2016). https://doi.org/10.1007/s10600-016-1606-7

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  • DOI: https://doi.org/10.1007/s10600-016-1606-7

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