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A New Rumenic Acid Derivative from the Roots of Cudrania tricuspidata

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Chemistry of Natural Compounds Aims and scope

A new rumenic acid derivative, threo-9,10-O-isopropylidene-13-hydroxy-(11E)-octadecenoic acid (1), and two known compounds, steppogenin (2) and oxyresveratrol (3), were isolated from the roots of Cudrania tricuspidata. The structure of the new compound was established by spectroscopic methods. All the compounds were evaluated for their cytotoxicity against three human tumor cell lines (HepG2, HCT-116, and SGC-7901). Unfortunately, none of them exhibited significant cytotoxicity at a concentration of 100 μM.

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Authors and Affiliations

  1. College of Biology and Environmental Engineering, Zhejiang Shuren University, 310015, Hangzhou, P. R. China

    Cheng-Ping Li

  2. College of Pharmaceutical Science, Zhejiang University of Technology, 310014, Hangzhou, P. R. China

    Cheng-Ping Li, Xiu-Juan Chang, Zha-Jun Zhan, You-Min Ying & Wei-Guang Shan

  3. Zhejiang Key Laboratory of Traditional Chinese Medicine Pharmaceutical Technology, Zhejiang CONBA Pharmaceutical Co. Ltd., 310052, Hangzhou, P. R. China

    Ling Fang, Jian-Biao Yao, Ru-Wei Wang & You-Min Ying

Authors
  1. Cheng-Ping Li
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  2. Xiu-Juan Chang
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  3. Ling Fang
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  4. Jian-Biao Yao
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  5. Ru-Wei Wang
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  6. Zha-Jun Zhan
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  7. You-Min Ying
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  8. Wei-Guang Shan
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Corresponding authors

Correspondence to You-Min Ying or Wei-Guang Shan.

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Li, CP., Chang, XJ., Fang, L. et al. A New Rumenic Acid Derivative from the Roots of Cudrania tricuspidata . Chem Nat Compd 52, 202–204 (2016). https://doi.org/10.1007/s10600-016-1594-7

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  • DOI: https://doi.org/10.1007/s10600-016-1594-7

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