A new cyclic peptide, cyclo(Leu-Val-Leu) (1), along with four known compounds (2–5), was isolated from the bulbs of Fritillaria hupehensis Hsiao and K.C. Hsia. The structure of compound 1 was elucidated by spectroscopic methods including 1D NMR and 2D NMR analyses as well as HR-ESI-MS techniques.
Similar content being viewed by others
References
J. Z. Wu, H. L. Ruan, C. L. Zeng, H. A. Cheng, F. Zhang, Q. S. Zhao, H. D. Sun, and T. Fujita, J. Asian Nat. Prod. Res., 1, 4 (1999).
G. Wang, J. G. Luo, M. H. Yang, X. B. Wang, and L. Y. Kong, Chem. Pharm. Bull., 61, 4 (2013).
C. M. Li, N. H. Tan, H. L. Zheng, Q. Mu, X. J. Hao, Y. N. He, and J. Zhou, Phytochemistry, 50, 6 (1999).
H. M. Xu, H. Yi, W. B. Zhou, W. J. He, G. Z. Zeng, W. Y. Xu, and N. H. Tan, Tetrahedron Lett., 54, 11 (2013).
B. S. Yun, I. J. Ryoo, I. K. Lee, and I. D. Yoo, Tetrahedron Lett., 39, 9 (1998).
Y. Tong, J. G. Luo, R. Wang, X. B. Wang, and L. Y. Kong, Bioorg. Med. Chem. Lett., 22, 5 (2012).
K. Fujii, Y. Ikai, H. Oka, M. Suzuki, and K. Harada, Anal. Chem., 69, 24 (1997).
B. S. Yun, I. J. Ryoo, I. K. Lee, and I. D. Yoo, Tetrahedron Lett., 54, 50 (1998).
J. M. Fang, C. K. Lee, and Y. S. Cheng, Phytochemistry, 33 (1993).
W. Goebel and H. Schrempf, J. Bacteriol., 111, 3 (1972).
S. L. Yang and X. K. Liu, Chin. J. Nat. Med., 1, 4 (2003) (in Chinese).
S. M. Zhou, K. Zhou, and D. J. Xiao, Chin. J. Mar. Drugs, 24, 4 (2005) (in Chinese).
Acknowledgment
This work was financially supported by the Fundamental Research Funds for the Central Universities (No. 2013QN009).
Author information
Authors and Affiliations
Corresponding author
Additional information
Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2015, pp. 792–793.
Rights and permissions
About this article
Cite this article
Tong, L., Zhu, Z., Pi, HF. et al. A New Cyclic Peptide from Bulbs of Fritillaria hupehensis . Chem Nat Compd 51, 923–925 (2015). https://doi.org/10.1007/s10600-015-1448-8
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10600-015-1448-8