The possibility of using the alkaloid aloperine for aminomethylation of a chromone ring was studied. A series of 8-(aloperin-12-yl)methyl-substituted isoflavone derivatives were synthesized.
Similar content being viewed by others
References
S. P. Bondarenko, M. S. Frasinyuk, V. I. Vinogradova, and V. P. Khilya, Chem. Nat. Compd., 46, 771 (2010).
S. P. Bondarenko, M. S. Frasinyuk, V. I. Vinogradova, and V. P. Khilya, Chem. Nat. Compd., 47, 604 (2011).
S. P. Bondarenko, M. S. Frasinyuk, A. I. Galaev, and V. I. Vinogradova, Chem. Nat. Compd., 48, 234 (2012).
A. Orechoff, N. Proskurnina, and R. Konowalowa, Chem. Ber., 68, 431 (1935).
T. E. Monakhova, O. N. Tolkachev, V. S. Kabanov, M. E. Perel'son, and N. F. Proskurnina, Chem. Nat. Compd., 10, 477 (1974).
O. N. Tolkachev, T. E. Monakhova, V. I. Sheichenko, V. S. Kabanov, O. G. Fesenko, and N. F. Proskurnina, Chem. Nat. Compd., 11, 29 (1975).
S. Kuchkarov, Y. K. Kushmuradov, and K. A. Aslanov, Chem. Nat. Compd., 13, 250 (1977).
S. Kuchkarov and Y. K. Kushmuradov, Chem. Nat. Compd., 15, 364 (1979).
A. D. Brosius and L. E. Overman, J. Org. Chem., 62, 440 (1997).
A. D. Brosius, L. E. Overman, and L. Schwink, J. Am. Chem. Soc., 121, 700 (1999).
D. Passarella, M. Angoli, A. Giardini, G. Lesma, A. Silvani, and B. Danieli, Org. Lett., 4, 2925 (2002).
A. Barilli, F. Belinghieri, D. Passarella, G. Lesma, S. Riva, A. Silvani, and B. Danieli, Tetrahedron: Asymmetry, 15, 2921 (2004).
C. C. Zhou, H. B. Gao, X. B. Sun, H. B. Shi, W. Liu, H. N. Yuan, and Z. X. Wang, Zhongguo Yaoli Xuebao, 10, 360 (1989).
X.-Y. Yuan, W. Liu, P. Zhang, R.-Y. Wang, and J.-Y. Guo, Eur. J. Pharmacol., 629, 147 (2010).
L. Zhang, Y. Zheng, H. Deng, L. Liang, and J. Peng, Int. J. Mol. Med., 33, 1613 (2014).
Z. Dang, K. Jung, L. Zhu, W. Lai, H. Xie, K.-H. Lee, L. Huang, and C.-H. Chen, ACS Med. Chem. Lett., 5, 942 (2014).
X.-N. Li, Z.-Q. Lu, S. Qin, H.-X. Yan, M. Yang, S.-H. Guan, X. Liu, H.-M. Hua, L.-J. Wu, and D.-A. Guo, Tetrahedron Lett., 49, 3797 (2008).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2015, pp. 554–556.
Rights and permissions
About this article
Cite this article
Bondarenko, S.P., Frasinyuk, M.S. & Khilya, V.P. Synthesis of Aloperine-Containing Mannich Bases of Isoflavones. Chem Nat Compd 51, 643–645 (2015). https://doi.org/10.1007/s10600-015-1375-8
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10600-015-1375-8