A new compound, isodihydroprehelminthosporol (1), and five known compounds, dihydroprehelminthosporol (2), 4-(2-hydroxyethyl)phenol (3), anhydrocochlioquinone A (4), isocochlioquinone A (5), and cochlioquinone A (6), were isolated from the fungus Veronaea sp. 1.03621. Their structures were elucidated using spectroscopic methods, mainly 1 D and 2 D NMR. These compounds were tested for their cytotoxicity towards two human cancer cell lines, A549 and SK-OA-3, and exhibited different activity.
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B. Schulz, C. Boyle, S. Draeger, A. K. Rommert, and K. Krohn, Mycol. Res., 106, 996 (2002).
R. N. Kharwar and R. K. Singh, Microbiol. Res., 159, 103 (2004).
L. M. Pena-Rodriguez, N. A. Armingeon, and W. S. Chilton, J. Nat. Prod., 51, 821 (1988).
F. Dorn and D. Arigoni, J. Chem. Soc. Chem. Commun., 24, 1342 (1972).
S. Christophoridou and P. Dais, Anal. Chim. Acta, 633, 283 (2009).
C. H. Lim, H. Miyagawa, M. Akamatsu, and Y. Nakagawa, J. Pesticide Sci., 23, 281 (1998).
P. Phuwapraisirisan, K. Sawang, P. Siripongc, and S. Tip-pyanga, Tetrahedron Lett., 48, 5193 (2007).
C. H. Yang, Y. Yang, and J. H. Liu, Phytochem. Lett., 6, 387 (2013).
J. M. Schaeffer, E. G. Frazier, A. R. Bergstrom, J. M. Williamson, J. M. Liesch, and M. A. Goetz, J. Antibiot., 43, 1179 (1990).
B. Bicalho, R. A. Goncalves, A. P. M. Zibordi, G. P. Manfio, and A. J. Marsaioli, Z. Naturforsch., 58c, 746 (2003).
T. Machida, K. Higashi, and H. Ogawara, J. Antibiot., 48, 1076 (1995).
Acknowledgment
The work was supported by Grants from the “973” Program of China (2013CB127505, 2012CB722208) and the NSFC (31360028), the Young Academic and Technical Leader Raising Foundation of Yunnan Province (2010CI023), and the China National Tobacco Corporation (110201002023).
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Published in Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2015, pp. 238–240.
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Zhou, L., Zheng, X., Wan, CP. et al. Chemical Constituents of the Fungus Veronaea sp.. Chem Nat Compd 51, 270–272 (2015). https://doi.org/10.1007/s10600-015-1259-y
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DOI: https://doi.org/10.1007/s10600-015-1259-y