Chemistry of Natural Compounds

, Volume 50, Issue 4, pp 589–593 | Cite as

1,5-DI-O-Isoferuloylquinic Acid and Other Phenolic Compounds from Pollen of Calendula officinalis

  • D. N. OlennikovEmail author
  • N. I. Kashchenko

A new phenylpropanoid that was identified as 1,5-di-O-isoferuloylquinic acid (1) and 17 known compounds including 1,5-di-O-feruloylquinic acid (2), which was obtained for the first time from a plant and was synthesized previously, were isolated from pollen of Calendula officinalis. Compounds 1 and 2 were the dominant phenolic compounds from pollen of C. officinalis. It was found that 1 possessed pronounced inhibitory activity against tyrosinase (IC50 11.26 μg/mL).


Calendula officinalis Asteraceae 1,5-di-O-isoferuloylquinic acid anti-tyrosinase activity 



The work was supported financially by the SB RAS program “Centers of New Medical Technologies.”


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Institute of General and Experimental Biology, Siberian BranchRussian Academy of SciencesUlan-UdeRussia

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