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New 12-N-β-Hydroxyethylcytisine Derivatives with Potential Antiarrhythmic Activity

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Chemistry of Natural Compounds Aims and scope

12-N-β-Hydroxyethylcytisine derivatives containing Cl, Br, and nitro groups on the 2-pyridone core were synthesized. Their antiarrhythmic activity was studied in vivo.

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Acknowledgment

The work was supported by RFBR Grant No. 12-03-00724-a and a grant of the RF President for Support of Leading Scientific Schools No. NSh-1700.2014.3.

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Authors and Affiliations

  1. Institute of Organic Chemistry, Ufa Scientific Center, Russian Academy of Sciences, 450054, Ufa, Prosp. Oktyabrya, 71, Russia

    I. P. Tsypysheva, A. V. Koval’skaya, R. Yu. Khisamutdinova, S. F. Gabdrakhmanova, A. N. Lobov, F. S. Zarudii & M. S. Yunusov

  2. Bashkir State University, 450000, Ul. Zaki Validi, 32, Ufa, Russia

    I. U. Khalilova & Yu. Yu. Bakhtina

  3. Bashkir State Medical University, 450000, Ufa, Ul. Lenina, 3, Russia

    F. S. Zarudii

Authors
  1. I. P. Tsypysheva
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  2. A. V. Koval’skaya
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  3. I. U. Khalilova
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  4. Yu. Yu. Bakhtina
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  5. R. Yu. Khisamutdinova
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  6. S. F. Gabdrakhmanova
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  7. A. N. Lobov
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  8. F. S. Zarudii
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  9. M. S. Yunusov
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Corresponding author

Correspondence to I. P. Tsypysheva.

Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2014, pp. 291–294.

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Tsypysheva, I.P., Koval’skaya, A.V., Khalilova, I.U. et al. New 12-N-β-Hydroxyethylcytisine Derivatives with Potential Antiarrhythmic Activity. Chem Nat Compd 50, 333–336 (2014). https://doi.org/10.1007/s10600-014-0945-5

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  • DOI: https://doi.org/10.1007/s10600-014-0945-5

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