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Modified Hyaluronic Acid as A Carrier of Mitomycin C for Ophthalmology

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Chemistry of Natural Compounds Aims and scope

Hyaluronic acid (HA) was modified chemically by epichlorohydrin in order to produce mitomycin conjugates. It was proved that complexes formed between mitomycin and modified HA and that modified HA reacted chemically with mitomycin upon heating.

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Authors and Affiliations

  1. Institute of Organic Chemistry, 450054, Russia, Republic of Bashkortostan, Ufa, Prosp. Oktyabrya, 71

    R. R. Vil’danova, N. N. Sigaeva, G. R. Fazylova, S. I. Kuznetsov & S. V. Kolesov

  2. Bashkir State University, 450076, Russia, Republic of Bashkortostan, Ufa, Ul. Z. Validi, 32

    O. S. Kukovinets

  3. Ufa Scientific Research Institute of Eye Diseases, Academy of Sciences of the Republic of Bashkortostan, 450008, Russia, Republic of Bashkortostan, Ufa, Ul. Pushkina, 90

    I. S. Zaidullin

Authors
  1. R. R. Vil’danova
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  2. N. N. Sigaeva
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  3. O. S. Kukovinets
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  4. I. S. Zaidullin
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  5. G. R. Fazylova
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  6. S. I. Kuznetsov
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  7. S. V. Kolesov
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Corresponding author

Correspondence to N. N. Sigaeva.

Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2014, pp. 205–207.

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Vil’danova, R.R., Sigaeva, N.N., Kukovinets, O.S. et al. Modified Hyaluronic Acid as A Carrier of Mitomycin C for Ophthalmology. Chem Nat Compd 50, 230–232 (2014). https://doi.org/10.1007/s10600-014-0919-7

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  • DOI: https://doi.org/10.1007/s10600-014-0919-7

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