Three compounds were isolated from the root barks of Periploca sepium. Their structures have been identified from physicochemical evidence and by spectral methods (MS, 2D NMR, and 1D TOCSY). These compounds are a new pregnane glycoside (periplocoside P) and two known oligosaccharides. Insecticidal activity bioassay showed that periplocoside P has insecticidal activity against the 3rd-instar larvae of Pseudaletia separata and Plutella xylostella. The LD50 values after 48 h were 10.8 and 3.6 μg · larva–1, respectively.
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Acknowledgment
The authors are grateful to Dr. Yi Hua (College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China) for the identification of the plant, and to Liu Zhenling and Liu Sunging (State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, Gansu, China) for NMR analysis. This research work was supported by the National Key S&T Research Foundation of China (2010CB126105) and the National Natural Science Foundation of China (31171868, 31071704).
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Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2013, pp. 895–898.
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Shi, Bj., Zhang, Jw., Gao, Lt. et al. A new pregnane glycoside from the root barks of Periploca sepium . Chem Nat Compd 49, 1043–1047 (2014). https://doi.org/10.1007/s10600-014-0819-x
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DOI: https://doi.org/10.1007/s10600-014-0819-x