Chemistry of Natural Compounds

, Volume 49, Issue 6, pp 1032–1034 | Cite as

Kaurane Diterpenoids from Celastrus orbiculatus

  • Jian-Juan Li
  • Jie Yang
  • Fei-Hua Wu
  • Shan-Shan Wang
  • Qiang WangEmail author

A new compound, ent-kaur-15-en-19,20-olide (1), together with a new natural compound, (–)-20-hydroxykaur16-en-19-oic acid lactone (2), were isolated from the stems of Celastrus orbiculatus Thunb. Their structures were determined by extensive analysis of spectroscopic data (1D and 2D NMR, MS) and by comparison with literature data.


Celastrus orbiculatus characterization kaurane diterpenoids cytotoxic activity 



The authors greatly appreciate the financial support from the priority academic program development of Jiangsu higher education institutions (PAPD) of China and the Social Development Project of Jiangsu Province of China (No. BE2011738). This work was also supported by the National Natural Science Foundation of China (No. 81102763 and 81373919).


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Jian-Juan Li
    • 1
  • Jie Yang
    • 1
  • Fei-Hua Wu
    • 2
  • Shan-Shan Wang
    • 2
  • Qiang Wang
    • 1
    Email author
  1. 1.State Key Laboratory of Natural MedicinesChina Pharmaceutical UniversityNanjingP. R. China
  2. 2.Department of Pharmacology for Chinese Materia MedicaChina Pharmaceutical UniversityNanjingP. R. China

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