Chemistry of Natural Compounds

, Volume 49, Issue 6, pp 991–995 | Cite as

Nitrogen–containing compounds from Hemerocallis fulva var. sempervirens


As part of our search for sedative substances derived from natural sources, two novel nitrogen compounds, kwansonine C (1) and oxypinnatanine A (2), and two novel salts of quinic acids (4) and (5) were isolated along with four known compounds, fulvanine A (3), icariside D2 (6), sallidroside (7), and (3S,4S)-3,4-dihydroxy-3-methyldihydrofuran-2-one (8), from Hemerocallis fulva L. var. sempervirens. These structures were elucidated by spectroscopic evidence and chemical methods.


Hemerocallis fulva var. sempervirens kwansonine C oxypinnatanine A 



The authors thank Ms. Kayoko Oda, Kyoto Pharmaceutical University, and Professor Naoki Noda, Faculty of Pharmaceutical Sciences, Setsunan University, for measurements of FAB-MS. This work was supported by a Grant-in Aid for Scientific Research (C) (No. 22590025) from the Japan Society for the Promotion of Science.


  1. 1.
    E. Uezu, Psychiatry Clin. Neurosci., 52, 136 (1998).PubMedCrossRefGoogle Scholar
  2. 2.
    Y. Ogawa and T. Konishi, Chem. Pharm. Bull., 57, 1110 (2009).PubMedCrossRefGoogle Scholar
  3. 3.
    T. Inoue, K. Iwagoe, T. Konishi, S. Kiyosawa, and Y. Fujiwara, Chem. Pharm. Bull., 38, 3187 (1990).CrossRefGoogle Scholar
  4. 4.
    T. Inoue, T. Konishi, S. Kiyosawa, and Y. Fujiwara, Chem. Pharm. Bull., 42, 154 (1994).CrossRefGoogle Scholar
  5. 5.
    L. Yun-Lian, L. Chung-Kuang, H. Yeh-Jeng, and C. Hong-Jhang, J. Agric. Food Chem., 59, 8789 (2011).CrossRefGoogle Scholar
  6. 6.
    Y. Guo, Y. Zhao, C. Zheng, Y. Meng, and Y. Yang, Chem. Pharm. Bull., 58, 1627 (2010).PubMedCrossRefGoogle Scholar
  7. 7.
    S. Nakamura, X. Li, H. Matsuda, and M. Yoshikawa, Chem. Pharm. Bull., 56, 536 (2008).PubMedCrossRefGoogle Scholar
  8. 8.
    P. Yu, C. Hu, E. J. Meehan, and L. Chen, Chem. Biodivers., 7, 508 (2007).CrossRefGoogle Scholar
  9. 9.
    S. Gogoi and N. P. Argade, Tetrahedron: Asymmetry, 17, 927 (2006).CrossRefGoogle Scholar
  10. 10.
    J. de P. Teresa, J. C. H. Aubanell, A. S. Feliciano, and J. M. del Corral, Tetrahedron Lett., 21, 1359 (1980).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Faculty of Pharmaceutical SciencesDoshisha Women’s College of Liberal ArtsKyotoJapan

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