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A new xanthone derivative from the marine fungus Phomopsis sp. (No. SK7RN3G1)

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Chemistry of Natural Compounds Aims and scope

A new xanthone, 2,6-dihydroxy-3-methyl-9-oxoxanthene-8-carboxylic acid methyl ester (1), and three known compounds were isolated from the marine fungus Phomopsis sp. (No. SK7RN3G1). Their structures were determined by spectroscopic methods, mainly 1D and 2D NMR. Primary bioassays showed that 1 exhibited cytotoxicity against HEp-2 and HepG2 cells with IC50 values of 8 and 9 μg/mL, respectively.

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Acknowledgment

We thank Prof. Lifu Wu and Dr. Jie Yuan for providing pharmacological data. This research was supported by the National Natural Science Foundation of China (20772162, 20972197), the 863 Foundation of China (2007AA09Z448, 2006AA09Z422), and the National Science Foundation of Guangdong Province, China (9151027501000055).

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Authors and Affiliations

  1. Key Laboratory of Plant Resources Conservation and Sustainable Utilization, Chinese Academy of Sciences, South China, Botanical Garden, 510650, Guangzhou, P. R. China

    Jian Xiang Yang & ShengXiang Qiu

  2. School of Chemistry and Chemical Engineering, Sun Yat-Sen University, 510275, Guangzhou, P. R. China

    Jian Xiang Yang, Zhigang She & Yongcheng Lin

Authors
  1. Jian Xiang Yang
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  2. ShengXiang Qiu
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  3. Zhigang She
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  4. Yongcheng Lin
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Corresponding authors

Correspondence to Jian Xiang Yang or ShengXiang Qiu.

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Published in Khimiya Prirodnykh Soedinenii, No. 1, January–February, 2013, pp. 30–31.

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Yang, J.X., Qiu, S., She, Z. et al. A new xanthone derivative from the marine fungus Phomopsis sp. (No. SK7RN3G1). Chem Nat Compd 49, 31–33 (2013). https://doi.org/10.1007/s10600-013-0498-z

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  • DOI: https://doi.org/10.1007/s10600-013-0498-z

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