The new ecdysteroid derivative 20-hydroxyecdysone O-(2-chloropyridin-5-ylmethyl)oxime (3) was synthesized via the reaction of 20-hydroxyecdysone (1) and O-(2-chloropyridin-5-ylmethyl)hydroxylamine (2) in Py in the presence of SnCl4.
Similar content being viewed by others
Explore related subjects
Discover the latest articles and news from researchers in related subjects, suggested using machine learning.References
N. V. Kovganko, S. N. Sokolov, Yu. G. Chernov, Zh. N. Kaskan, and V. L. Survilo, Khim. Prir. Soedin., 632 (2010).
A. A. Akhrem and N. V. Kovganko, Ecdysteroids: Chemistry and Biological Activity [in Russian], Nauka i Tekhnika, Minsk, 1989.
V. V. Volodin (ed.), Phytoecdysteroids [in Russian], Nauka, St. Petersburg, 2003.
I. V. Galyautdinov, N. A. Ves’kina, S. R. Afon’kina, L. M. Khalilov, and V. N. Odinokov, Zh. Org. Khim., 42, 1352 (2006).
L. Reum and J. Koolman, in: Ecdysone from Chemistry to Mode of Action, J. Koolman, J. Becker, P. Karlson, et al. (eds.), G. Thieme Verlag, Stuttgart, New York, 1989, pp. 131–143.
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2011, pp. 825–827.
Rights and permissions
About this article
Cite this article
Kovganko, N.V., Ananich, S.K., Sokolov, S.N. et al. Synthesis of the O-(2-chloropyridin-5-ylmethyl)oxime of 20-hydroxyecdysone. Chem Nat Compd 47, 944–946 (2012). https://doi.org/10.1007/s10600-012-0110-y
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10600-012-0110-y

