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Synthesis and crystal structure of N(12)-(2-hydroxy-2-phenylethyl)cytisine

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Diastereomers of N(12)-(2-hydroxy-2-phenylethyl)cytisine were synthesized by reduction of N(12)-(2-oxo-2-phenylethyl)cytisine by Yamamoto reagent. Their structures were solved using x-ray structure analysis.

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References

  1. K. D. Berlin, G. L. Garrison, S. Sangiah, G. R. Clarke, C. Chen, R. Lazzara, B. J. Scherlag, E. S. Patterson,and G. E. Burrows, U.S. Pat. No. 5,468,858 (1995); Ref. Zh. Khim., 8O70P (1997).

  2. N. N. Yarmukhamedov, L. T. Karachurina, R. Yu. Khisamutdinova, F. S. Zarudii, N. Z. Baibulatova, F. N. Dzhakhangirov, V. A. Dokichev, Yu. V. Tomilov, M. S. Yunusov, and O. M. Nefedov, RF Pat. No. 2,228,179 (2004); Byull. Izobret., No. 13 (2004).

  3. R. Yu. Khisamutdinova, N. N. Yarmukhamedov, S. F. Gabdrakhmanova, L. T. Karachurina, T. A. Sapozhnikova, N. Z. Baibulatova, N. Zh. Baschenko, and F. S. Zarudii, Khim.-farm. Zh., 38, 27 (2004).

    Google Scholar 

  4. D. V. Shishkin, A. R. Shaimuratova, A. N. Lobov, N. Z. Baibulatova, L. V. Spirikhin, M. S. Yunusov, N. S. Makara, N. Zh. Baschenko, and V. A. Dokichev, Khim. Prir. Soedin., 157 (2007).

  5. Z. Liu, L. Yang, Z. Jia, and J. Chen, Magn. Reson. Chem., 30, 511 (1992).

    Article  CAS  Google Scholar 

  6. H. P. Hamlow, S. Okuda, and N. Nakagawa, Tetrahedron Lett., 5, 2553 (1964).

    Article  Google Scholar 

  7. B. Mikhova and H. Duddeck, Magn. Reson. Chem., 36, 779 (1998).

    Article  Google Scholar 

  8. F. Bohlmann, Chem. Ber., 91, 2157 (1958).

    Article  CAS  Google Scholar 

  9. D. V. Shishkin, E. R. Mukhamed′yarova, N. Z. Baibulatova, V. A. Dokichev, and Yu. V. Tomilov, Khim. Prir. Soedin., 244 (2007).

  10. S. Iguchi, H. Nakai, M. Hayashi, H. Yamamoto, and K. Maruoka, Bull. Chem. Soc. Jpn., 54, 3033 (1981).

    Article  CAS  Google Scholar 

  11. G. M. Sheldrick, SHELXTL, v. 5.10, Structure Determination Software Suite, Bruker AXS Inc., Madison, Wisconsin 53719, USA, 1998.

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Correspondence to V. A. Dokichev.

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Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 56–58, January–February, 2010.

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Shishkin, D.V., Baibulatova, N.Z., Lobov, A.N. et al. Synthesis and crystal structure of N(12)-(2-hydroxy-2-phenylethyl)cytisine. Chem Nat Compd 46, 62–65 (2010). https://doi.org/10.1007/s10600-010-9525-5

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  • DOI: https://doi.org/10.1007/s10600-010-9525-5

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