The composition of the lipophilic extract of the sponge Myrmekioderma granulata (Esper) collected from 13 m depth of the Bay of Bengal of the Orissa coast was investigated. Fatty acids as well as volatiles and sterols were identified. 4,8,12-Trimethyltridecanoic acid was identified for the first time along with the important PUFAs such as linoleic acid (n-6, C18:2), dihomo-γ-linolenic acid (n-6, C20:3), 5,8,11,14-eicosatetraenoic acid (n-3, C20:4), and 5,8,11,14,17-eicosapentaenoic acid (EPA) (n-3, C20:5) from this species. The branched polyunsaturated fatty acids like br-C26:2, 25-methyl-5,9-heptacosadienoic acid and 24-methyl-5,9heptacosadienoic acid were also identified by GC-MS. The lipid extract exhibited limited activity against different pathogens.
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References
J. Peng, K. Walsh, V. Weedman, J. D. Bergthold, J. Lynch, L. Lieuk, I. A. Braude, M. Kelly, and M. T. Hamann,Tetrahedron, 58, 809 (2002).
V. V. Sova, T. G. Svetasheva, and L. A. Elyakova, Chem. Nat. Comp., 24, 481 (1989).
H. Li Kam Wah, S. Jhaumeer-Laulloo, R. Choong Kwet Yive, I. Bonnard, B. Banaigs, and D. Marie, Western Indian Ocean J. Mar. Sci., 5, 115 (2006).
Y. Letourneux, J. M. Brunel, R. Fernandez, M. Dherbomez, and C. Debitus, Heterocycl. Commun., 11, 291 (2005).
S. Aoki, K. Higuchi, K. A. Kato, N. Murakami, and M. Kobayashi, Tetrahedron, 55, 14865 (1999).
M. Nestor, Elba D. Reyes Carballeira, and Fathi Shalabi, J. Nat. Prod., 56, 1850 (1993).
T. Kaneda, Microb. Rev., 55, 288 (1991).
P. R. Bergquist, M. P. Lawson, A. Lavis, and R. C. Cambie, Biochem. Syst. Ecol., 12, 63 (1984).
S. De Rosa, S. De Caro, G. Tommonaro, K. Slantchev, K. Stefanov, and S. Popov, Mar. Biol., 140, 465 (2002).
D. Sica, F. De Simone, E. Ramundo, and F. Zollo, Biochem. Syst. Ecol., 6, 77 (1978).
Ts. Milkova, S. Popov, N. Marekov, and St. Andreev, Comp. Biochem. Physiol., B 67, 633 (1980).
M. O. Fatope, O. A. Adoum, and Y. Takeda, J. Agr. Food Chem., 48, 1872 (2000).
H. Galbraith and T. B. Miller, J. Appl. Bacteriol., 36, 635 (1973).
D. D. Carson and L. Daneo-Moore, J. Bacteriol., 141, 1122 (1980).
K. Mohan Rao, K. S. R. Murthy, N. P. C. Reddy, A. S. Subrahmanyam, S. Lakshinarayan, M. K. Prem Kumar, K. V. L. N. Sarma, Y. S. N. Raju, A. Sree, and M. Bapuji, Curr. Sci., 81, 828 (2001).
K. V. L. N. Sarma, Y. S. N. Raju, A. Sree, and M. Bapuji, Curr. Sci., 81, 828 (2001).
J. Folch, M. Lees, and G. H. S. Stanely, J. Biol. Chem., 226, 497 (1957).
H. Hendriks, J. Geerts, and Th. Malingre, Pharm. Weekblad. Sci., 116, 1316 (1981).
J. F. Acar, The Disc Susceptibility Test: Antibiotics in Laboratory Medicine, Lorian V (ed), Williams and Wilkins, Baltimore, London, 1980, pp. 24–54.
Acknowledgment
The authors thank Prof. B. K. Mishra, Director, RRL, Bhubaneswar for providing facilities, Dr. P. A. Thomas, Ex-Emeritus Scientist, Central Marine Fisheries Research Institute (ICAR), Vizhinjam, Trivandrum, Kerala for identification of the sponge, the Department of Ocean development (DOD) for funding the project and the Indian Navy for SCUBA diving assistance to collect marine organisms. Two of us (P. M. Mishra & S. Baliarsingh) thank DOD for research fellowship.
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Published in Khimiya Prirodnykh Soedinenii, No. 5, pp. 525– 527, September–October, 2009.
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Manjari Mishra, P., Sree, A. & Baliarsingh, S. Antibacterial study and fatty acid analysis of lipids of the sponge Myrmekioderma granulata . Chem Nat Compd 45, 621–624 (2009). https://doi.org/10.1007/s10600-009-9445-4
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DOI: https://doi.org/10.1007/s10600-009-9445-4