Skip to main content
SpringerLink
Log in

Synthesis and antituberculosis activity of certain steroidal derivatives of the 5α-series

  • Published:
Chemistry of Natural Compounds Aims and scope

The antituberculosis activity of several steroidal compounds of various structure was studied. Severa compounds that were active toward M. tuberculosis were found in in vitro tests.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. M. I. Merlani, V. I. Sladkov, N. I. Men′shova, L. N. Filitis, E. P. Kemertelidze, and N. N. Suvorov, Soobshch. Akad. Nauk Gruz., 153, 763 (1995).

    Google Scholar 

  2. M. I. Merlani, E. P. Kemertelidze, K. Papadopulos, and N. I. Men′shova, Bioorg. Khim., 30, 552 (2004).

    PubMed  CAS  Google Scholar 

  3. M. I. Merlani, L. Sh. Amiranashvili, M. G. Davitishvili, E. P. Kemertelidze, K. Papadopulos, and E. Yannakopulu, Khim. Prir. Soedin., 160 (2006).

  4. S. M. Newton, C. Lau, and C. W. Wright, Phytother. Res., 14, 303 (2000).

    Article  PubMed  CAS  Google Scholar 

  5. J. Gatfield and J. Pieters, Science, 288, 1647 (2000).

    Article  PubMed  CAS  Google Scholar 

  6. J. K. Ruggut, C. W. Henry, S. G. Franzblau, and I. M. Warner, J. Agric. Food Chem., 47, 3402 (1999).

    Article  Google Scholar 

  7. M. I. Merlani, V. I. Sladkov, V. A. Parshin, N. I. Men′shova, I. I. Levina, and N. N. Suvorov, Khim.-farm. Zh., 23, 1431 (1989).

    CAS  Google Scholar 

  8. M. I. Merlani, L. Sh. Amiranashvili, E. P. Kemertelidze, K. Papadopulos, and E. Yannakopulu, Khim. Prir. Soedin., 257 (2006).

  9. L. Sh. Amiranashvili, V. I. Sladkov, I. I. Levina, N. I. Men′shova, and N. N. Suvorov, Zh. Org. Khim., 26, 1884 (1990).

    CAS  Google Scholar 

Download references

Acknowledgment

We thank Dr. Kishor Bhat from Maratha Mandal’s Dental College Belgaum (India) for performing the antituberculosis tests.

Author information

Authors and Affiliations

  1. I. G. Kutateladze Institute of Pharmaceutical Chemistry, Academy of Sciences of Georgia, 0159, ul. Saradzhishvili, 36, Tbilisi, Georgia

    M. I. Merlani, L. Sh. Amiranashvili & K. G. Mulkidzhanyan

  2. Pharmaceutical College, University KLES, Belgaum-10, India

    A. R. Shelar & F. V. Manvi

Authors
  1. M. I. Merlani
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. Sh. Amiranashvili
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. K. G. Mulkidzhanyan
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. R. Shelar
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. F. V. Manvi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to M. I. Merlani.

Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 500–501, September-October, 2008. Original article submitted July 10, 2008.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Merlani, M.I., Amiranashvili, L.S., Mulkidzhanyan, K.G. et al. Synthesis and antituberculosis activity of certain steroidal derivatives of the 5α-series. Chem Nat Compd 44, 618–620 (2008). https://doi.org/10.1007/s10600-008-9126-8

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10600-008-9126-8

Key words

Search

Navigation