Abstract
Five new compounds, orizaterpenol (1), orizaterpenoid (2), orizaterpenyl benzoate (3), orizanor-diterpenyl benzoate (4), and orizaditerpenyl benzoate (5), along with nine known compounds, were isolated and identified from the rice hulls of Oryza sativa. Their structures were elucidated with the help of different spectroscopic techniques. Orizaterpenol (1) and the known momilactone A (6) and B (7) were found to have cytotoxic effects against P388 murine leukaemia cells, while the other new and known compounds exhibited weak cytotoxicity.
Similar content being viewed by others
REFERENCES
A. K. Dutta, Ind. J. Agric., 42, 984 (1973).
K. Ishizumi, Textbook of Rice Cultivars, Fului Nojyo Kankobu, p. 52 (1989).
T. Kato, C. Kabuto, N. Sasaki, M. Tsunagawa, H. Aizawa, K. Fujita, Y. Kato, and Y. Kitahara, Tetrahedron Lett., 39, 3861 (1973).
T. Kato, M. Tsunakawa, N. Sasaki, H. Aizawa, K. Fujita, Y. Kitahara, and N. Takahashi, Phytochemistry, 16, 45 (1977).
N. Takahashi, T. Kato, M. Tsunagawa, N. Sasaki, and Y. Kitahara, 1976, Jap. J. Plant Breed., 26, 91 (1976).
H. Kato-Nahuchi, T. Ino, N. Sata, S. Yamamura, Physiologia Plantarum, 115, 401 (2002).
N. Ramarathnam, T. Osawa, M. Namiki, and S. Kawakishii, J. Agric. Food Chem, 36, 732 (1988).
N. Ramarathnam, T. Osawa, M. Namiki, and S. Kawakishii, J. Agric. Food Chem., 37, 316 (1989).
P. K. Agrawal, Phytochemistry, 31, 3307 (1992).
P. K. Agrawal, V. Bishnoi, and A. K. Singh, Phytochemistry, 39, 929 (1995).
Y. Chen, Z. Wu, Y. Lu, S. Gui, J. Wen, X. Liao, L. Yuan, and F. Halaweish, Arch. Pharm. Res., 26, 912 (2003).
H. S. Park, N. Yoda, Y. Naoki, H. Fukaya, Y. Aoyagi, and K. Takeya, Tetrahedron, 60, 171 (2004).
Author information
Authors and Affiliations
Additional information
__________
Published in Khimiya Prirodnykh Soedinenii, No. 2, pp. 146–151, March–April, 2005.
Rights and permissions
About this article
Cite this article
Chung, I.M., Ali, M., Hahn, S.J. et al. Chemical Constituents from the Hulls of Oryza sativa with Cytotoxic Activity. Chem Nat Compd 41, 182–189 (2005). https://doi.org/10.1007/s10600-005-0108-9
Received:
Issue Date:
DOI: https://doi.org/10.1007/s10600-005-0108-9