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Composition and Antimicrobial Activity of Helichrysum italicum Essential Oil and Its Terpene and Terpenoid Fractions

Chemistry of Natural Compounds volume 41, pages 35–40 (2005)Cite this article

Abstract

The essential oil of Helichrysum italicum (Roth) G. Don from Croatia has been fractionated into terpene and terpenoid fractions and analyzed using GC/MS. Fifty-two compounds were identified. The main hydrocarbons of the oil were α-pinene (10.2%), α-cedrene (9.6%) aromadendrene (4.4%), β-caryophyllene (4.2%), and limonene (3.8%), while the main oxygen-containing compounds were neryl acetate (11.5%), 2-methylcyclohexyl pentanoate (8.3%), 2-methylcyclohexyl octanoate (4.8%), and geranyl acetate (4.7%). The essential oil and its terpene and terpenoid fractions were evaluated for antibacterial and antifungal activities. The screening of antimicrobial activity was conducted by a disc diffusion test and the minimum inhibitory concentration was determined against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans. The essential oil and its terpenoid fraction exhibited higher antimicrobial activity with respect to the terpene fraction. The antimicrobial activities of the oil and its terpenoid fraction were more pronounced against Staphylococcus aureus and Candida albicans.

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Authors and Affiliations

  1. Department of Organic Chemistry and Natural Products, Faculty of Chemical Technology, University of Split, N. Tesle 10/V, 21000, Split, Croatia

    J. Mastelic & I. Jerkovic

  2. Department of Biochemistry and Food Chemistry, Faculty of Chemical Technology, University of Split, N. Tesle 10/V, 21000, Split, Croatia

    O. Politeo

  3. Institute of Naval Medicine, University of Split, Soltanska 1, 21000, Split, Croatia

    N. Radosevic

Authors
  1. J. Mastelic
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  2. O. Politeo
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  3. I. Jerkovic
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  4. N. Radosevic
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Published in Khimiya Prirodnykh Soedinenii, No. 1, pp. 29–32, January–February, 2005.

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Mastelic, J., Politeo, O., Jerkovic, I. et al. Composition and Antimicrobial Activity of Helichrysum italicum Essential Oil and Its Terpene and Terpenoid Fractions. Chem Nat Compd 41, 35–40 (2005). https://doi.org/10.1007/s10600-005-0069-z

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  • DOI: https://doi.org/10.1007/s10600-005-0069-z

Key words

  • Helichrysum italicum
  • essential oil
  • terpene and terpenoid fractions
  • GC/MS
  • antimicrobial activity